Skip to search formSkip to main contentSkip to account menu

Thrombopoiesis

Known as: thrombocyte differentiation, Thrombocytopoiesis, platelet production 
The process of generating thrombocytes (BLOOD PLATELETS) from the pluripotent HEMATOPOIETIC STEM CELLS in the BONE MARROW via the MEGAKARYOCYTES. The… 
National Institutes of Health

Related topics

Related topics

15 relations
Blood CellsBlood PlateletsMPL geneMPL protein, human

Broader (1)

Hematopoiesis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
PLATELETS AND THROMBOPOIESIS Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac 1 and Cdc 42
University of Würzburg, Department of Experimental Biomedicine, University Hospital and Rudolf Virchow Center, Deutsche… 
Highly Cited
2012
Highly Cited
2012
Multiploid CD61+ Cells Are the Pre-Dominant Cell Lineage Infected during Acute Dengue Virus Infection in Bone Marrow
Depression of the peripheral blood platelet count during acute infection is a hallmark of dengue. This thrombocytopenia has been… 
Highly Cited
1996
Highly Cited
1996
Constitutive expression of Mpl ligand transcripts during thrombocytopenia or thrombocytosis.
Mpl ligand (thrombopoietin [TPO]) is the physiological regulator of platelet production. In mice, mRNA encoding the Mpl ligand… 
Highly Cited
1996
Highly Cited
1996
Deletion of the acetylcholinesterase locus at 7q22 associated with myelodysplastic syndromes (MDS) and acute myeloid leukaemia (AML).
Highly Cited
1986
Highly Cited
1986
Chromosome 3q21 abnormalities associated with hyperactive thrombopoiesis in acute blastic transformation of chronic myeloid leukemia.
Two patients with acute blastic transformation of chronic myeloid leukemia (CML) associated with strikingly elevated platelet… 
Highly Cited
1985
Highly Cited
1985
Platelet and Megakaryocyte Changes in Cholesterol‐Induced Experimental Atherosclerosis
Rabbits were fed either 2 g cholesterol in 10 ml olive oil daily with normal diet (n = 5) or normal diet alone (n = 5). After 12… 
Highly Cited
1984
Highly Cited
1984
Thrombocytopoiesis--analysis by membrane tracer and freeze-fracture studies on fresh human and cultured mouse megakaryocytes
The origin of platelets (Pt) from megakaryocytes (MK) is beyond question, but the mechanism whereby Pts are released from the… 
Highly Cited
1971
Highly Cited
1971
Platelet Volume: Density Relationships in Normal and Acutely Bled Dogs
The relationship between platelet volume and platelet density was studied in normal dogs and in dogs subjected to acute blood… 
Highly Cited
1967
Highly Cited
1967
Regulation of Platelet Production: ‘Thrombopoietin’
Plasma from thrombocytopenic animals induces thrombocytosis in normal recipients. Thrombocytopenia induced by platelet antiserum… 
Highly Cited
1955
Highly Cited
1955
The dynamics of platelet production as studied by a depletion technique in normal and irradiated dogs.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)