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Thrombopoiesis
Known as:
thrombocyte differentiation
, Thrombocytopoiesis
, platelet production
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The process of generating thrombocytes (BLOOD PLATELETS) from the pluripotent HEMATOPOIETIC STEM CELLS in the BONE MARROW via the MEGAKARYOCYTES. The…
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National Institutes of Health
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Related topics
Related topics
15 relations
Blood Cells
Blood Platelets
MPL gene
MPL protein, human
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Broader (1)
Hematopoiesis
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
PLATELETS AND THROMBOPOIESIS Defective tubulin organization and proplatelet formation in murine megakaryocytes lacking Rac 1 and Cdc 42
Irina Pleines
,
Sebastian Dütting
,
+9 authors
B. Nieswandt
2013
Corpus ID: 206919580
University of Würzburg, Department of Experimental Biomedicine, University Hospital and Rudolf Virchow Center, Deutsche…
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Highly Cited
2012
Highly Cited
2012
Multiploid CD61+ Cells Are the Pre-Dominant Cell Lineage Infected during Acute Dengue Virus Infection in Bone Marrow
K. Clark
,
S. Noisakran
,
+5 authors
G. Perng
PLoS ONE
2012
Corpus ID: 3875687
Depression of the peripheral blood platelet count during acute infection is a hallmark of dengue. This thrombocytopenia has been…
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Highly Cited
1996
Highly Cited
1996
Constitutive expression of Mpl ligand transcripts during thrombocytopenia or thrombocytosis.
K. Cohen-Solal
,
J. Villeval
,
M. Titeux
,
S. Lok
,
W. Vainchenker
,
Frangoise Wendling
Blood
1996
Corpus ID: 25031681
Mpl ligand (thrombopoietin [TPO]) is the physiological regulator of platelet production. In mice, mRNA encoding the Mpl ligand…
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Highly Cited
1996
Highly Cited
1996
Deletion of the acetylcholinesterase locus at 7q22 associated with myelodysplastic syndromes (MDS) and acute myeloid leukaemia (AML).
J. Stephenson
,
B. Czepulkowski
,
W. Hirst
,
G. Mufti
Leukemia research : a Forum for Studies on…
1996
Corpus ID: 31558725
Highly Cited
1986
Highly Cited
1986
Chromosome 3q21 abnormalities associated with hyperactive thrombopoiesis in acute blastic transformation of chronic myeloid leukemia.
R. Bernstein
,
A. Bagg
,
M. Pinto
,
D. Lewis
,
B. Mendelow
Blood
1986
Corpus ID: 18298365
Two patients with acute blastic transformation of chronic myeloid leukemia (CML) associated with strikingly elevated platelet…
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Highly Cited
1985
Highly Cited
1985
Platelet and Megakaryocyte Changes in Cholesterol‐Induced Experimental Atherosclerosis
J. Martin
,
D. Slater
,
Y. Kishk
,
E. Trowbridge
Arteriosclerosis
1985
Corpus ID: 2137791
Rabbits were fed either 2 g cholesterol in 10 ml olive oil daily with normal diet (n = 5) or normal diet alone (n = 5). After 12…
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Highly Cited
1984
Highly Cited
1984
Thrombocytopoiesis--analysis by membrane tracer and freeze-fracture studies on fresh human and cultured mouse megakaryocytes
Dorothea Zucker-Franklin
Journal of Cell Biology
1984
Corpus ID: 9982991
The origin of platelets (Pt) from megakaryocytes (MK) is beyond question, but the mechanism whereby Pts are released from the…
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Highly Cited
1971
Highly Cited
1971
Platelet Volume: Density Relationships in Normal and Acutely Bled Dogs
F. M. Minter
,
M. Ingram
British Journal of Haematology
1971
Corpus ID: 38890961
The relationship between platelet volume and platelet density was studied in normal dogs and in dogs subjected to acute blood…
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Highly Cited
1967
Highly Cited
1967
Regulation of Platelet Production: ‘Thrombopoietin’
G. Gabriele
,
D. Penington
British Journal of Haematology
1967
Corpus ID: 35722028
Plasma from thrombocytopenic animals induces thrombocytosis in normal recipients. Thrombocytopenia induced by platelet antiserum…
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Highly Cited
1955
Highly Cited
1955
The dynamics of platelet production as studied by a depletion technique in normal and irradiated dogs.
C. Craddock
,
W. S. Adams
,
S. Perry
,
J. Lawrence
Journal of Laboratory and Clinical Medicine
1955
Corpus ID: 42775530
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