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MPL gene

Known as: THROMBOPOIETIN RECEPTOR, MPL, MPLV 
This gene plays a regulatory role in megakaryocytopoiesis and platelet formation.
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Polycythemia vera (PV) is characterized by JAK2 and essential thrombocythemia (ET) by JAK2, calreticulin (CALR), and… Expand
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Highly Cited
2014
Highly Cited
2014
Janus kinase 2 (JAK2) mutations define polycythemia vera (PV). Calreticulin (CALR) and myeloproliferative leukemia virus oncogene… Expand
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2014
2014
Thrombopoietin (TPO) acting via its receptor, the cellular homologue of the myeloproliferative leukemia virus oncogene (Mpl), is… Expand
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Highly Cited
2013
Highly Cited
2013
We studied mutations of MPL exon 10 in patients with essential thrombocythemia (ET) or primary myelofibrosis (PMF), first… Expand
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Highly Cited
2012
Highly Cited
2012
Researchers have successfully applied exome sequencing to discover causal variants in selected individuals with familial, highly… Expand
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2011
2011
BACKGROUND Mutations in the thrombopoietin receptor (MPL) may activate relevant pathways and lead to chronic myeloproliferative… Expand
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Highly Cited
2010
Highly Cited
2010
The 46/1 JAK2 haplotype predisposes to V617F-positive myeloproliferative neoplasms, but the underlying mechanism is obscure. We… Expand
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1994
1994
The human c-mpl proto-oncogene encodes a member of the cytokine receptor superfamily, expressed mainly in CD 34-positive… Expand
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1993
1993
The v-mpl oncogene transduced in the myeloproliferative leukemia virus (MPLV) encodes a truncated form of a putative receptor… Expand
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Highly Cited
1990
Highly Cited
1990
The myeloproliferative leukemia virus (MPLV) is an acute leukemogenic murine replication-defective retrovirus. By sequencing the… Expand
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