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Methylation of cytosines at CpG sites is a common epigenetic DNA modification that can be measured by a large number of methods… Expand Circadian (∼24 hour) clocks are fundamentally important for coordinated physiology in organisms as diverse as cyanobacteria and… Expand PURPOSE
To update the 2000 American Society of Clinical Oncology guideline on the use of hematopoietic colony-stimulating factors… Expand All blood cell lineages derive from a common hematopoietic stem cell (HSC). The current model implicates that the first lineage… Expand Chronic myeloid leukemia (CML) is probably the most extensively studied human malignancy. The discovery of the Philadelphia (Ph… Expand Stem cells are found in various organs where they participate in tissue homeostasis by replacing differentiated cells lost to… Expand MANY STUDIES HAVE led to the concept that membrane phospholipid asymmetry is ubiquitous. In general terms, the outer leaflet of… Expand We explicitly acknowledge key intellectual contributions from Jody Rosenblatt (depolymerization) and Julie Theriot (protrusion… Expand Mouse bone marrow hematopoietic stem cells were isolated with the use of a variety of phenotypic markers. These cells can… Expand The elucidation of the molecular architecture of cell membranes is a central goal for cell biology, as structure lies at the… Expand