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Thalassemia

Known as: Thalassemia, unspecified, syndromes thalassemia, Thalassemia [Disease/Finding] 
A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic… 
National Institutes of Health

Related topics

Related topics

25 relations
AnemiaBart's HemoglobinopathyHematological DiseaseHematopoietic and Lymphoid Cell

Broader (2)

Anemia, Hemolytic, CongenitalHemoglobinopathies

Narrower (6)

Cooley's anemiaHemoglobin F DiseaseHereditary persistence of fetal hemoglobin thalassemiaThalassemia Minor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
HEALTH AND DEMOGRAPHIC SURVEILLANCE SYSTEM PROFILE Profile: The Kilifi Health and Demographic Surveillance System (KHDSS)
The Kilifi Health and Demographic Surveillance System (KHDSS), located on the Indian Ocean coast of Kenya, was established in… 
Review
2010
Review
2010
Paraspinal extramedullary hematopoiesis in patients with thalassemia intermedia
Ineffective erythropoiesis in patients with thalassemia intermedia drives extramedullary hematopoietic tumor formation in several… 
Review
2006
Review
2006
Oral chelators deferasirox and deferiprone for transfusional iron overload in thalassemia major: new data, new questions.
For nearly 30 years, patients with transfusional iron overload have depended on nightly deferoxamine infusions for iron chelation… 
Review
2006
Review
2006
Stiffness of normal and pathological erythrocytes studied by means of atomic force microscopy.
Highly Cited
2006
Highly Cited
2006
Oxidative stress and inflammation in iron‐overloaded patients with β‐thalassaemia or sickle cell disease
Blood transfusion therapy is life‐saving for patients with β‐thalassaemia and sickle cell disease (SCD), but often results in… 
Highly Cited
2003
Highly Cited
2003
Metabolic and endocrinologic complications in beta-thalassemia major: a multicenter study in Tehran
BackgroundThe combination of transfusion and chelation therapy has dramatically extended the life expectancy of thalassemic… 
Review
1999
Review
1999
Red blood cell membrane disorders
The recent discovery of the specific molecular defects in many patients with hereditary spherocytosis and hereditary… 
Highly Cited
1982
Highly Cited
1982
A single-base change at a splice site in a β0-thalassemic gene causes abnormal RNA splicing
Highly Cited
1974
Highly Cited
1974
Long-term Chelation Therapy in Thalassaemia Major: Effect on Liver Iron Concentration, Liver Histology, and Clinical Progress
A prospective trial of continuous chelation therapy in children with homozygous thalassaemia on a high transfusion regimen was… 
Highly Cited
1969
Highly Cited
1969
Effect of flavin compounds on glutathione reductase activity: in vivo and in vitro studies.
Increases or decreases of red cell glutathione reductase (GR) have been described in connection with many clinical abnormalities… 
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