Thalassemia

Known as: Thalassemia, unspecified, syndromes thalassemia, Thalassemia [Disease/Finding] 
A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic… (More)
National Institutes of Health

Papers overview

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Review
2017
Review
2017
BACKGROUND Haemoglobinopathies constitute the commonest recessive monogenic disorders worldwide, and the treatment of affected… (More)
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Review
2011
Review
2011
The purpose of this article is to set forth our approach to diagnosing and managing the thalassemias, including β-thalassemia… (More)
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Highly Cited
2007
Highly Cited
2007
In thalassemia, deficient globin-chain production during erythropoiesis results in anemia. Thalassemia may be further complicated… (More)
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Highly Cited
2006
Highly Cited
2006
Deferasirox (ICL670) is a once-daily oral iron chelator developed for the treatment of chronic iron overload from blood… (More)
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Highly Cited
2005
Highly Cited
2005
Measurements of hepatic iron concentration (HIC) are important predictors of transfusional iron burden and long-term outcome in… (More)
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Highly Cited
2005
Highly Cited
2005
Deferoxamine (DFO) therapy has been associated with improved survival of thalassemia patients. However, cardiac disease remains… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND AND OBJECTIVES Seven Italian centers reported data on survival, causes of death and appearance of complications in… (More)
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Review
1997
Review
1997
Iron-chelating therapy with deferoxamine in patients with thalassemia major has dramatically altered the prognosis of this… (More)
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Highly Cited
1995
Highly Cited
1995
The ATR-X syndrome is an X-linked disorder comprising severe psychomotor retardation, characteristic facial features, genital… (More)
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Highly Cited
1994
Highly Cited
1994
BACKGROUND To determine whether deferoxamine prevents the complications of transfusional iron overload in thalassemia major, we… (More)
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