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Tenecteplase

Known as: t-plasminogen activator, TNK-tPA, tPA 
A 527 amino acid glycoprotein and the modified form of the naturally occurring human plasminogen activator (tPA) with tissue plasminogen activating… Expand
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
BACKGROUND The role of fibrinolytic therapy in patients with intermediate-risk pulmonary embolism is controversial. METHODS In… Expand
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Highly Cited
2014
Highly Cited
2014
BACKGROUND Acute pulmonary embolism (PE) can worsen quality of life due to persistent dyspnea or exercise intolerance… Expand
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Highly Cited
2012
Highly Cited
2012
BACKGROUND Intravenous alteplase is the only approved treatment for acute ischemic stroke. Tenecteplase, a genetically engineered… Expand
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Highly Cited
2010
Highly Cited
2010
INTRODUCTION The clinical benefit of thrombolytic treatment over heparin in patients with pulmonary embolism without hemodynamic… Expand
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Highly Cited
2010
Highly Cited
2010
Background and Purpose— Intravenous alteplase (rtPA) remains the only approved treatment for acute ischemic stroke, but its use… Expand
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Highly Cited
2005
Highly Cited
2005
Background and Purpose— Recombinant tissue-type plasminogen activator (rtPA) is the only approved treatment in acute ischemic… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Current fibrinolytic therapies fail to achieve optimum reperfusion in many patients. Low-molecular-weight heparins and… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND Bolus fibrinolytic therapy facilitates early efficient institution of reperfusion therapy. Tenecteplase is a… Expand
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Highly Cited
1999
Highly Cited
1999
Summary Background Bolus fibrinolytic therapy facilitates early efficient institution of reperfusion therapy. Tenecteplase is a… Expand
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