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alteplase

Known as: T-Plasminogen Activator, Tissue Activator D 44, TPA 
A recombinant therapeutic agent which is chemically identical to or similar to endogenous tissue plasminogen activator (tPA). tPA is a serine… 
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Background and Purpose— The purpose of these guidelines is to provide an up-to-date comprehensive set of recommendations for… 
Highly Cited
2015
Highly Cited
2015
BACKGROUND Among patients with acute ischemic stroke due to occlusions in the proximal anterior intracranial circulation, less… 
Highly Cited
2008
Highly Cited
2008
BACKGROUND Intravenous thrombolysis with alteplase is the only approved treatment for acute ischemic stroke, but its efficacy and… 
Highly Cited
1999
Highly Cited
1999
ContextIntravenous tissue-type plasminogen activator can be beneficial to some patients when given within 3 hours of stroke onset… 
Highly Cited
1998
Highly Cited
1998
BACKGROUND Thrombolysis for acute ischaemic stroke has been investigated in several clinical trials, with variable results. We… 
Highly Cited
1996
Highly Cited
1996
BACKGROUND Thrombolytic therapy for acute ischemic stroke has been approached cautiously because there were high rates of… 
Highly Cited
1993
Highly Cited
1993
BACKGROUND The relative efficacy of streptokinase and tissue plasminogen activator and the roles of intravenous as compared with…