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Leptin resistance: underlying mechanisms and diagnosis
TLDR
This review of existing data on the methods used to diagnose leptin resistance encompasses a complex pathophysiological phenomenon with a number of potential research lines.
Recombinant urokinase is safe and effective in restoring patency to occluded central venous access devices: A multiple-center, international trial*?
TLDR
This multiple-center, open-label study was performed to test the hypothesis that a new recombinant urokinase (r-UK) is safe and effective in reestablishing patency in a large unselected cohort of occluded CVADs.
Localization of fat depots and cardiovascular risk
TLDR
This review aims to discuss the contemporary literature regarding the characteristics of the visceral, epicardial, and perivascular fat depots, as well as their associations with cardiovascular disease.
[Evaluation of coronary artery lesion in men with osteopenic syndrome and coronary artery disease].
TLDR
Severe CB lesion in males correlates with CAC and is associated with decreased BMD, suggesting the commonness of the pathogenetic components of AS and OS.
Genomic structural variations for cardiovascular and metabolic comorbidity
The objective of this study was to identify genes targeted by both copy number and copy-neutral changes in the right coronary arteries in the area of advanced atherosclerotic plaques and intact
Adipokine and Cytokine Profiles of Epicardial and Subcutaneous Adipose Tissue in Patients with Coronary Heart Disease
TLDR
In epicardial adipocytes of coronary heart disease patients, the concentrations of leptin, TNF-α, and IL-1 were higher, while the levels of defense regulatory molecules were lower than in subcutaneous adipocytes.
A Comparison of Genome-Wide DNA Methylation Patterns between Different Vascular Tissues from Patients with Coronary Heart Disease
TLDR
The DNA methylation differences observed in vascular tissues of patients with coronary heart disease can provide new insights into the mechanisms underlying the development of pathology and explanation for the difference in graft patency after coronary artery bypass grafting surgery.
[Prognostic factors in patients with non-ST-segment elevation acute coronary syndrome concurrent with type 2 diabetes mellitus (according to the results of the registry)].
TLDR
The register-based study has shown that the presence of DM2 statistically significantly increases cardiovascular mortality rates during a year after the index ACS event; the patients of this category are less commonly referred for CA for the estimation of the degree of coronary bed lesion.
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