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Telomere Capping

Known as: telomere end protection 
A process in which telomeres are protected from degradation and fusion, thereby ensuring chromosome stability by protecting the ends from both… 
National Institutes of Health

Related topics

Related topics

20 relations
Cell SurvivalG22P1 wt AlleleKu ProteinPOT1 gene

Narrower (1)

telomeric 3' overhang formation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Telomere capping in Drosophila: dealing with chromosome ends that most resemble DNA breaks
Telomere caps prevent chromosome ends from being recognized as DNA double-strand breaks (DSBs). Unlike most organisms studied… 
Highly Cited
2007
Highly Cited
2007
The Role of Stn1p in Saccharomyces cerevisiae Telomere Capping Can Be Separated From Its Interaction With Cdc13p
The function of telomeres is twofold: to facilitate complete chromosome replication and to protect chromosome ends against… 
2006
2006
Linear chromosome maintenance in the absence of essential telomere-capping proteins
Telomeres were defined by their ability to cap chromosome ends. Proteins with high affinity for the structure at chromosome ends… 
2005
2005
A Mutation in the STN1 Gene Triggers an Alternative Lengthening of Telomere-Like Runaway Recombinational Telomere Elongation and Rapid Deletion in Yeast
ABSTRACT Some human cancer cells achieve immortalization by using a recombinational mechanism termed ALT (alternative lengthening… 
Highly Cited
2004
Highly Cited
2004
Role of Human Ku86 in Telomere Length Maintenance and Telomere Capping
The role of Ku86 at telomeres has been extensively studied in various organisms; however, a role for Ku86 at human telomeres was… 
2004
2004
Genetic Dissection of the Kluyveromyces lactis Telomere and Evidence for Telomere Capping Defects in TER1 Mutants with Long Telomeres
ABSTRACT In the yeast Kluyveromyces lactis, the telomeres are composed of perfect 25-bp repeats copied from a 30-nucleotide RNA… 
2004
2004
Pol12, the B subunit of DNA polymerase , functions in both telomere capping and length regulation
The regulation of telomerase action, and its coordination with conventional DNA replication and chromosome end “capping,” are… 
2003
2003
The Rad51 Pathway of Telomerase-Independent Maintenance of Telomeres Can Amplify TG1-3 Sequences in yku and cdc13 Mutants of Saccharomyces cerevisiae
ABSTRACT In the yeast Saccharomyces cerevisiae, Cdc13, Yku, and telomerase define three parallel pathways for telomere end… 
Highly Cited
2003
Highly Cited
2003
Resistance to the Short Term Antiproliferative Activity of the G-quadruplex Ligand 12459 Is Associated with Telomerase Overexpression and Telomere Capping Alteration*
Ligands that stabilize the telomeric G-rich single-stranded DNA overhang into G-quadruplex can be considered as potential… 
Review
1993
Review
1993
Telomeres and their possible role in chromosome stabilization
The evidence to date generally supports the hypothesis that telomere capping makes chromosome fragments refractory to subsequent… 
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