Telomere Capping

Known as: telomere end protection 
A process in which telomeres are protected from degradation and fusion, thereby ensuring chromosome stability by protecting the ends from both… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Rap1 is a component of the shelterin complex at mammalian telomeres, but its in vivo role in telomere biology has remained… (More)
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Highly Cited
2008
Highly Cited
2008
The budding yeast Cdc13, Stn1 and Ten1 (CST) proteins are proposed to function as an RPA-like complex at telomeres that protects… (More)
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Highly Cited
2004
Highly Cited
2004
HP1 is a conserved chromosomal protein, first discovered in Drosophila, which is predominantly associated with the… (More)
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Highly Cited
2004
Highly Cited
2004
Telomeres are protective structures at chromosome ends and are crucial for genomic stability. Mammalian TRF1 and TRF2 bind the… (More)
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Highly Cited
2003
Highly Cited
2003
HOAP (HP1/ORC-associated protein) has recently been isolated from Drosophila melanogaster embryos as part of a cytoplasmic… (More)
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Highly Cited
2002
Highly Cited
2002
Telomeres allow cells to distinguish natural chromosome ends from damaged DNA. When telomere function is disrupted, a potentially… (More)
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Highly Cited
2001
Highly Cited
2001
The DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is critical for DNA repair via the nonhomologous end joining… (More)
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Highly Cited
2001
Highly Cited
2001
In Saccharomyces cerevisiae, Cdc13 has been proposed to mediate telomerase recruitment at telomere ends. Stn1, which associates… (More)
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Highly Cited
2000
Highly Cited
2000
Telomeres are specialized DNA/protein structures that act as protective caps to prevent end fusion events and to distinguish the… (More)
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Review
1996
Review
1996
Telomeres are the components of chromosome ends that provide stability and allow the complete replication of the ends. Telomere… (More)
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