Ku Protein

Known as: Lupus Autoantigen, Lupus Ku Autoantigen, Ku 
A DNA damage repair complex that, with the 470-kDa DNA-dependent protein kinase catalytic subunit (DNA-PKcs) protein, is part of the DNA-dependent… (More)
National Institutes of Health

Papers overview

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Highly Cited
2001
Highly Cited
2001
A paramount role of telomeres is to prevent chromosome fusions. The fission yeast Taz1 protein regulates diverse telomere… (More)
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Highly Cited
2000
Highly Cited
2000
Mammalian nonhomologous DNA end joining employs Ku70, Ku80, DNA-dependent protein kinase catalytic subunit (DNA-PKcs), XRCC4, and… (More)
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Highly Cited
2000
Highly Cited
2000
Non-homologous DNA end joining (NHEJ) is considered the major pathway of double-strand break (DSB) repair in mammalian cells and… (More)
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Highly Cited
1999
Highly Cited
1999
Yku70p/Yku80p, the yeast Ku protein homologue, is a DNA end-binding heterodimer involved in non-homologous end joining. It also… (More)
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Highly Cited
1999
Highly Cited
1999
Ku protein and the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) are essential components of the double-strand break… (More)
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Highly Cited
1998
Highly Cited
1998
Ku protein binds to DNA ends and is a cofactor for the DNA-dependent protein kinase. Both of these components are involved in DNA… (More)
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Highly Cited
1998
Highly Cited
1998
The first protein that binds to all newly synthesized RNA polymerase III transcripts is a highly conserved phosphoprotein known… (More)
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Highly Cited
1997
Highly Cited
1997
Although the La autoantigen binds to the 3' ends of all nascent polymerase III transcripts, its function in vivo has long been… (More)
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Highly Cited
1996
Highly Cited
1996
DNA double-strand break (DSB) repair in mammalian cells is dependent on the Ku DNA binding protein complex. However, the… (More)
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1994
1994
The human autoantigen La is a 50-kDa protein which binds to the 3' termini of virtually all nascent polymerase III transcripts… (More)
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