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TSLP gene

Known as: THYMIC STROMAL LYMPHOPOIETIN, TSLP, Thymic Stromal Lymphopoietin Gene 
This gene plays a regulatory role in the development of B lymphocytes.
National Institutes of Health

Related topics

Related topics

9 relations
Cytokine Receptor BindingCytokine SignalingHematopoiesisImmunoregulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Emerging monoclonal antibodies as targeted innovative therapeutic approaches to asthma
Asthma is characterized by discordant responses among cells of the adaptive and innate immune systems. This interplay involves a… 
2015
2015
Murine allergic rhinitis and nasal Th2 activation are mediated via TSLP- and IL-33-signaling pathways.
Thymic stromal lymphopoietin (TSLP) and IL-33 are epithelium-derived proallergic cytokines that contribute to allergic diseases… 
2014
2014
Induction of innate immunity by Aspergillus fumigatus cell wall polysaccharides is enhanced by the composite presentation of chitin and beta-glucan.
Review
2013
Review
2013
Virus/Allergen Interactions in Asthma
Understanding the underlying mechanisms that cause and exacerbate allergic asthmatic disease is of great clinical interest… 
Highly Cited
2009
Highly Cited
2009
TSLP production by epithelial cells exposed to immunodeficiency virus triggers DC-mediated mucosal infection of CD4+ T cells
Mucosal dendritic cells have been implicated in the capture, storage, and transmission of HIV to CD4+ T cells as well as in the… 
2009
2009
The Hedgehog receptor Patched1 regulates myeloid and lymphoid progenitors by distinct cell-extrinsic mechanisms.
Hedgehog (Hh) ligands bind to the Patched1 (Ptch1) receptor, relieving repression of Smoothened, which leads to activation of the… 
Highly Cited
2008
Highly Cited
2008
Thymic Stromal Lymphopoietin and Thymic Stromal Lymphopoietin–Conditioned Dendritic Cells Induce Regulatory T-Cell Differentiation and Protection of NOD Mice Against Diabetes
OBJECTIVE—Autoimmune diabetes in the nonobese diabetic (NOD) mouse model results from a breakdown of T-cell tolerance caused by… 
Highly Cited
2008
Highly Cited
2008
Cutting Edge: Inhibition of NF-κB-Mediated TSLP Expression by Retinoid X Receptor1
The epithelial-derived cytokine thymic stromal lymphopoietin (TSLP) has important roles in the initiation of allergic airway… 
Highly Cited
2007
Highly Cited
2007
Thymic stromal-derived lymphopoietin induces proliferation of pre-B leukemia and antagonizes mTOR inhibitors, suggesting a role for interleukin-7Ralpha signaling.
Understanding the pathogenesis of leukemia in the context of lymphopoiesis may reveal novel therapeutic targets. Previously, we… 
2004
2004
Overexpression of murine TSLP impairs lymphopoiesis and myelopoiesis.
The role of thymic stromal cell-derived lymphopoietin (TSLP) in regulating hematopoiesis is poorly characterized, so we… 
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