Author pages are created from data sourced from our academic publisher partnerships and public sources.
- Publications
- Influence
Immunological aspects of allergic asthma.
- B. Bochner, B. Undem, L. Lichtenstein
- Medicine
- Annual review of immunology
- 1994
Asthma is a chronic obstructive disease of the lower airways. It is characterized by episodic exacerbations of at least partially reversible airflow limitation, along with bronchial hyperreactivity… Expand
Refining the definition of hypereosinophilic syndrome.
- H. Simon, M. Rothenberg, +7 authors A. Klion
- Medicine
- The Journal of allergy and clinical immunology
- 1 July 2010
Because of advances in our understanding of the hypereosinophilic syndrome (HES) and the availability of novel therapeutic agents, the original criteria defining these disorders are becoming… Expand
Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy.
- P. Ogbogu, B. Bochner, +17 authors A. Klion
- Medicine
- The Journal of allergy and clinical immunology
- 1 December 2009
BACKGROUND
Hypereosinophilic syndrome (HES) is a heterogeneous group of rare disorders defined by persistent blood eosinophilia > or =1.5 x 10(9)/L, absence of a secondary cause, and evidence of… Expand
Approaches to the treatment of hypereosinophilic syndromes: a workshop summary report.
- A. Klion, B. Bochner, +5 authors P. Weller
- Medicine
- The Journal of allergy and clinical immunology
- 1 June 2006
Hypereosinophilic syndromes are a heterogeneous group of uncommon disorders characterized by the presence of marked peripheral blood eosinophilia, tissue eosinophilia, or both, resulting in a wide… Expand
Glycan Array Screening Reveals a Candidate Ligand for Siglec-8*
- B. Bochner, R. Álvarez, +4 authors R. Schnaar
- Chemistry, Medicine
- Journal of Biological Chemistry
- 11 February 2005
Sialic acid-binding immunoglobulin-like lectin 8 (Siglec-8) is selectively expressed on human eosinophils, basophils, and mast cells, where it regulates their function and survival. Previous studies… Expand
Variants of thymic stromal lymphopoietin and its receptor associate with eosinophilic esophagitis.
- Joseph D Sherrill, P. Gao, +14 authors M. Rothenberg
- Biology, Medicine
- The Journal of allergy and clinical immunology
- 1 July 2010
BACKGROUND
The genetic cause of eosinophilic esophagitis (EE) has been largely unexplored until a recent genome-wide association study identified a disease susceptibility locus on 5q22, a region that… Expand
Adhesion of human basophils, eosinophils, and neutrophils to interleukin 1-activated human vascular endothelial cells: contributions of endothelial cell adhesion molecules
- B. Bochner, F. Luscinskas, +5 authors R. Schleimer
- Biology, Medicine
- The Journal of experimental medicine
- 1 June 1991
Cytokines such as interleukin 1 (IL-1) promote adhesiveness in human umbilical vein endothelial cells for leukocytes including basophils, eosinophils, and neutrophils, and induce expression of… Expand
Down-regulation of Fc(epsilon)RI expression on human basophils during in vivo treatment of atopic patients with anti-IgE antibody.
- D. Macglashan, B. Bochner, +6 authors L. Lichtenstein
- Chemistry, Medicine
- Journal of immunology
- 1 February 1997
Treatment of allergic disease by decreasing circulating IgE with anti-IgE Abs is currently under clinical study. Based on previous unrelated studies, it appeared likely that Fc(epsilon)RI expression… Expand
Ligation of Siglec-8: a selective mechanism for induction of human eosinophil apoptosis.
- E. Nutku, H. Aizawa, S. Hudson, B. Bochner
- Biology, Medicine
- Blood
- 15 June 2003
Sialic acid binding immunoglobulin-like lectin 8 (Siglec-8), which exists in 2 isoforms including one possessing cytoplasmic tyrosine motifs, is expressed only on human eosinophils, basophils, and… Expand
Risk assessment in anaphylaxis: current and future approaches.
- F. Simons, A. Frew, +13 authors A. Walls
- Medicine
- The Journal of allergy and clinical immunology
- 1 July 2007
Risk assessment of individuals with anaphylaxis is currently hampered by lack of (1) an optimal and readily available laboratory test to confirm the clinical diagnosis of an anaphylaxis episode and… Expand