TP73 gene

Known as: P73, TUMOR PROTEIN p73, TP73 
This gene is involved in the apoptotic pathway and can have anti or pro apoptotic effects.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-2018
05019842018

Papers overview

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Highly Cited
2005
Highly Cited
2005
The recently discovered p53-related genes, p73 and p63, express multiple splice variants and N-terminally truncated forms… (More)
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Highly Cited
2005
Highly Cited
2005
p63 and p73 are functionally and structurally related to the tumor suppressor p53. However, their own role in tumor suppression… (More)
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Highly Cited
2003
Highly Cited
2003
Most chemotherapeutic agents induce DNA damage, leading to p53 accumulation and apoptosis. The factors that determine… (More)
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Highly Cited
2002
Highly Cited
2002
The tumour-suppressor gene p53 is frequently mutated in human cancers and is important in the cellular response to DNA damage… (More)
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Highly Cited
2001
Highly Cited
2001
The p53 protein is related by sequence homology and function to the products of two other genes, p63 and p73, that each encode… (More)
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Highly Cited
2000
Highly Cited
2000
p73 (ref. 1) has high homology with the tumour suppressor p53 (refs 2,3,4), as well as with p63, a gene implicated in the… (More)
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Highly Cited
2000
Highly Cited
2000
p53 plays an essential pro-apoptotic role, a function thought to be shared with its family members p73 and p63. Here, we show… (More)
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Highly Cited
1999
Highly Cited
1999
Cancer chemotherapeutic agents such as cisplatin exert their cytotoxic effect by inducing DNA damage and activating programmed… (More)
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Highly Cited
1999
Highly Cited
1999
The protein p73 is a structural and functional homologue of the p53 tumour-suppressor protein but, unlike p53, it is not induced… (More)
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Highly Cited
1997
Highly Cited
1997
We describe a gene encoding p73, a protein that shares considerable homology with the tumor suppressor p53. p73 maps to 1p36, a… (More)
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