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TP73 gene

Known as: P73, TUMOR PROTEIN p73, TP73 
This gene is involved in the apoptotic pathway and can have anti or pro apoptotic effects.
National Institutes of Health

Related topics

Related topics

7 relations
ApoptosisNeuroblastomaPositive Regulation of ApoptosisTranscriptional Regulation

Papers overview

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Highly Cited
2011
Highly Cited
2011
Synergistic Effects of the Green Tea Extract Epigallocatechin-3-gallate and Taxane in Eradication of Malignant Human Prostate Tumors.
We have examined whether epigallocatechin-3-gallate (EGCG), and extract of green tea, in combination with taxane (i.e… 
Review
2004
Review
2004
p53 protein variants: structural and functional similarities with p63 and p73 isoforms
Since its discovery in 1979, many studies have reported that the p53 tumour suppressor protein could be expressed in the form of… 
Highly Cited
2003
Highly Cited
2003
Identification of Daxx interacting with p73, one of the p53 family, and its regulation of p53 activity by competitive interaction with PML.
We performed a yeast two-hybrid screen using p73alpha, which is a member of the p53 family, as bait. We found that the p53 family… 
Highly Cited
2001
Highly Cited
2001
Genomic approaches to elucidation of the Fhit pathway in worms and yeast: Rosetta Stone and synthetic lethals
Genomic approaches to elucidation of the Fhit pathway in worms and yeast: Rosetta Stone and synthetic lethals 
Highly Cited
2000
Highly Cited
2000
P73 gene expression in ovarian cancer tissues and cell lines.
Thep73 gene, a homology of p53, is a new candidate of imprinting and tumor suppressor gene. To investigate the role of p73 in… 
Highly Cited
1999
Highly Cited
1999
Distinct Regulation of p53 and p73 Activity by Adenovirus E1A, E1B, and E4orf6 Proteins
ABSTRACT Multiple adenovirus (Ad) early proteins have been shown to inhibit transcription activation by p53 and thereby to alter… 
Highly Cited
1999
Highly Cited
1999
Comparative Analysis of P73 and P53 Regulation and Effector Functions
p53 is mutated in ∼50% of human cancers, whereas mutations of the related p73 gene are rare. p73 can activate p53-responsive… 
Highly Cited
1999
Highly Cited
1999
Elevated and biallelic expression of p73 is associated withprogression of human bladder cancer.
p73, a member of the p53 family at 1p36.3, has been demonstrated to be expressed monoallelically and induce apoptosis or G1… 
Highly Cited
1998
Highly Cited
1998
p73beta, unlike p53, suppresses growth and induces apoptosis of human papillomavirus E6-expressing cancer cells.
Human papillomavirus (HPV) is the major cause of cervical cancer worldwide. HPV-E6 protein targets the p53 tumor suppressor… 
Highly Cited
1985
Highly Cited
1985
Structural analysis of the varicella-zoster virus gp98-gp62 complex: posttranslational addition of N-linked and O-linked oligosaccharide moieties
Varicella-zoster virus specifies the formation of several glycoproteins, including the preponderant gp98-gp62 glycoprotein… 
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