TNFSF11 protein, human

Known as: RANKL, osteoprotegerin ligand, human, OPGL 
Tumor necrosis factor ligand superfamily member 11 (317 aa, ~35 kDa) is encoded by the human TNFSF11 gene. This protein is involved in osteoclast… (More)

Topic mentions per year

Topic mentions per year

1989-2017
010203019892017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Osteoclasts are the only somatic cells with bone-resorbing capacity and, as such, they have a critical role not only in normal… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
In the present study, we examined the expression of regulators of bone formation and osteoclastogenesis in human atherosclerosis… (More)
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2000
Highly Cited
2000
Osteoprotegerin-ligand (OPGL) is a key osteoclast differentiation/activation factor essential for bone remodeling. We report that… (More)
  • figure 1
  • figure 4
  • figure 6
  • figure 7
Is this relevant?
Highly Cited
2000
Highly Cited
2000
High systemic levels of osteoprotegerin (OPG) in OPG transgenic mice cause osteopetrosis with normal tooth eruption and bone… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1999
Highly Cited
1999
The tumour-necrosis-factor-family molecule osteoprotegerin ligand (OPGL; also known as TRANCE, RANKL and ODF) has been identified… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
Bone remodelling and bone loss are controlled by a balance between the tumour necrosis factor family molecule osteoprotegerin… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
The ligand for osteoprotegerin has been identified, and it is a TNF-related cytokine that replaces the requirement for stromal… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Osteoclast differentiation factor (ODF) is a ligand for osteoclastogenesis-inhibitory factor/osteoprotegerin (OCIF/OPG), and… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
TRANCE (tumor necrosis factor [TNF]-related activation-induced cytokine) is a new member of the TNF family that is induced upon T… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • figure 5
Is this relevant?
Highly Cited
1997
Highly Cited
1997
A novel member of the tumor necrosis factor (TNF) cytokine family, designated TRANCE, was cloned during a search for apoptosis… (More)
Is this relevant?