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TNFSF11 protein, human

Known as: RANKL, osteoprotegerin ligand, human, OPGL 
Tumor necrosis factor ligand superfamily member 11 (317 aa, ~35 kDa) is encoded by the human TNFSF11 gene. This protein is involved in osteoclast… 
National Institutes of Health

Related topics

Related topics

17 relations
ApoptosisApoptosis Regulatory ProteinsBone Remodelling PathwayCell Death

Broader (1)

TRANCE protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Nrf2 deficiency induces oxidative stress and promotes RANKL-induced osteoclast differentiation.
Highly Cited
2011
Highly Cited
2011
A microRNA expression signature of osteoclastogenesis.
MicroRNAs (miRs) are small noncoding RNAs that principally function in the spatiotemporal regulation of protein translation in… 
Highly Cited
2009
Highly Cited
2009
Central control of fever and female body temperature by RANKL/RANK
Receptor-activator of NF-κB ligand (TNFSF11, also known as RANKL, OPGL, TRANCE and ODF) and its tumour necrosis factor (TNF… 
Highly Cited
2008
Highly Cited
2008
Berberine inhibits RANKL-induced osteoclast formation and survival through suppressing the NF-kappaB and Akt pathways.
Highly Cited
2002
Highly Cited
2002
MLO‐Y4 Osteocyte‐Like Cells Support Osteoclast Formation and Activation
Osteocytes are terminally differentiated cells of the osteoblast lineage that have become embedded in mineralized matrix and may… 
Highly Cited
2001
Highly Cited
2001
Tumor Necrosis Factor-α (TNF) Stimulates RANKL-induced Osteoclastogenesis via Coupling of TNF Type 1 Receptor and RANK Signaling Pathways*
Tumor necrosis factor-α (TNF) and the ligand for receptor activator of NF-κB (RANKL) are abundant in sites of inflammatory bone… 
Highly Cited
2000
Highly Cited
2000
Trance, a Tumor Necrosis Factor Family Member, Enhances the Longevity and Adjuvant Properties of Dendritic Cells in Vivo
Mature dendritic cells (DCs) are powerful antigen presenting cells that have the unique capacity to migrate to the T cell zone of… 
Highly Cited
2000
Highly Cited
2000
Regulation of Peripheral Lymph Node Genesis by the Tumor Necrosis Factor Family Member Trance
Proper lymph node (LN) development requires tumor necrosis factor–related activation-induced cytokine (TRANCE) expression. Here… 
Review
2000
Review
2000
Bone loss: Factors that regulate osteoclast differentiation - an update
Osteoclast activation is a critical cellular process for pathological bone resorption, such as erosions in rheumatoid arthritis… 
Highly Cited
1979
Highly Cited
1979
Trance and Treatment–Clinical Uses of Hypnosis
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