TNFRSF10A gene

Known as: TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 10A, TRAILR1, DR4 
This gene is involved in cell death signal transduction and apoptosis mediation.
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Cell-surface death receptors such as DR4 and DR5 trigger apoptosis through a death-inducing signaling complex (DISC) that… (More)
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Highly Cited
2007
Highly Cited
2007
APOBEC-2 (APO2) belongs to the family of apolipoprotein B messenger RNA-editing enzyme catalytic (APOBEC) polypeptides, which… (More)
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Highly Cited
2003
Highly Cited
2003
Myeloma cells grow only in the bone marrow closely associated with bone,suggesting that this microenvironment provides critical… (More)
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Highly Cited
2002
Highly Cited
2002
Interleukin-6 (IL-6) and insulin-like growth factor-1 (IGF-1) promote the proliferation of multiple myeloma (MM) cells and… (More)
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Highly Cited
2002
Highly Cited
2002
The importance of Bax for induction of tumor apoptosis through death receptors remains unclear. Here we show that Bax can be… (More)
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Highly Cited
2001
Highly Cited
2001
It has been reported that interferons (IFNs) may have antitumor activity in multiple myeloma (MM). The mechanism for their effect… (More)
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Highly Cited
2001
Highly Cited
2001
Apo2 ligand tumor necrosis factor-related apoptosis-inducing ligand (Apo2L/TRAIL) is a member of the tumor necrosis factor family… (More)
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Highly Cited
2000
Highly Cited
2000
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) (Apo2 ligand [Apo2L]) is a member of the TNF superfamily… (More)
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Highly Cited
2000
Highly Cited
2000
Cellular resistance to multiple proapoptotic stimuli and invasion of surrounding brain tissue by migrating tumor cells are main… (More)
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Highly Cited
1999
Highly Cited
1999
TNF and Fas ligand induce apoptosis in tumor cells; however, their severe toxicity toward normal tissues hampers their… (More)
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