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TNF receptor-associated factor 5

Known as: TNF Receptor Associated Protein 5, TNF Receptor Associated Factor 5, TNF Receptor-Associated Factor 5 [Chemical/Ingredient] 
A signal transducing tumor necrosis factor receptor associated factor that mediates signaling from CD27 ANTIGENS; CD40 ANTIGENS; and the LYMPHOTOXIN… Expand
National Institutes of Health

Related topics

Related topics

11 relations

Broader (1)

Carrier Proteins
In BloodProcess of secretionTNF receptor-associated factor 4TRAF5 gene
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma
Diffuse large B-cell lymphoma (DLBCL), the most common form of lymphoma in adulthood, comprises multiple biologically and… Expand
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Highly Cited
2006
Highly Cited
2006
Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif
Upon recognition of viral infection, RIG‐I and Helicard recruit a newly identified adapter termed Cardif, which induces type I… Expand
Highly Cited
2003
Highly Cited
2003
NF‐κB inhibits TNF‐induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death
NF‐κB downregulates tumor necrosis factor (TNF)‐induced c‐Jun N‐terminal kinase (JNK) activation that promotes cell death, but… Expand
Review
2001
Review
2001
Tumor necrosis factor receptor-associated factors (TRAFs)
Tumor necrosis factor receptor-associated factors (TRAFS) were initially discovered as adaptor proteins that couple the tumor… Expand
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Highly Cited
1999
Highly Cited
1999
Activation of NF-kappaB by RANK requires tumor necrosis factor receptor-associated factor (TRAF) 6 and NF-kappaB-inducing kinase. Identification of a novel TRAF6 interaction motif.
Various members of the tumor necrosis factor (TNF) receptor superfamily activate nuclear factor kappaB (NF-kappaB) and the c-Jun… Expand
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Highly Cited
1998
Highly Cited
1998
NF-κB-inducing kinase activates IKK-α by phosphorylation of Ser-176
Activation of the transcription factor NF-κB by inflammatory cytokines involves the successive action of NF-κB-inducing kinase… Expand
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Highly Cited
1998
Highly Cited
1998
The TRAF Family of Signal Transducers Mediates NF-κB Activation by the TRANCE Receptor*
Tumor necrosis factor (TNF)-related activation-induced cytokine (TRANCE), a member of the TNF family expressed on activated T… Expand
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Highly Cited
1998
Highly Cited
1998
ASK1 is essential for JNK/SAPK activation by TRAF2.
Tumor necrosis factor (TNF)-induced activation of the c-jun N-terminal kinase (JNK, also known as SAPK; stress-activated protein… Expand
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Highly Cited
1998
Highly Cited
1998
RIP2 is a novel NF-kappaB-activating and cell death-inducing kinase.
Through specific interactions with members of the tumor necrosis receptor (TNFR) family, adapter molecules such as the serine… Expand
Highly Cited
1996
Highly Cited
1996
Identification of TRAF6, a Novel Tumor Necrosis Factor Receptor-associated Factor Protein That Mediates Signaling from an Amino-terminal Domain of the CD40 Cytoplasmic Region*
CD40 signalings play crucial roles in B-cell function. To identify molecules which transduce CD40 signalings, we have utilized… Expand
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