FAQ

TNF receptor-associated factor 5

Known as: TNF Receptor Associated Protein 5, TNF Receptor Associated Factor 5, TNF Receptor-Associated Factor 5 [Chemical/Ingredient] 
A signal transducing tumor necrosis factor receptor associated factor that mediates signaling from CD27 ANTIGENS; CD40 ANTIGENS; and the LYMPHOTOXIN… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2018
051019962018

Related topics

Related topics

13 relations

Broader (1)

Carrier Proteins
In BloodProcess of secretionTNF receptor-associated factor 4TRAF5 gene
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
TNF receptor-associated factor 5
physiological aspects
agonists
Carrier Proteins
chemical synthesis
standards characteristics

Papers overview

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2013
2013
TNF receptor-associated factor 5 gene confers genetic predisposition to acute anterior uveitis and pediatric uveitis
INTRODUCTION TNF Receptor-Associated Factor 5 (TRAF5) has been shown to be associated with autoimmune disease. The current study… (More)
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2004
2004
TNF receptor-associated factor 5 limits the induction of Th2 immune responses.
The TNF receptor-associated factor (TRAF) family of molecules acts as adapter proteins for signaling pathways initiated by… (More)
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Highly Cited
2003
Highly Cited
2003
NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death.
NF-kappaB downregulates tumor necrosis factor (TNF)-induced c-Jun N-terminal kinase (JNK) activation that promotes cell death… (More)
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2003
2003
TNF-related weak inducer of apoptosis receptor, a TNF receptor superfamily member, activates NF-kappa B through TNF receptor-associated factors.
TNF-related weak inducer of apoptosis (TWEAK) is a member of the TNF ligand family that induces angiogenesis in vivo. The TWEAK… (More)
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Highly Cited
2000
Highly Cited
2000
The atypical PKC-interacting protein p62 channels NF-kappaB activation by the IL-1-TRAF6 pathway.
The atypical protein kinase C (aPKC)-interacting protein, p62, has previously been shown to interact with RIP, linking these… (More)
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1999
1999
Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1)
Tumor necrosis factor-α (TNF), a major inflammatory cytokine, generates a wide variety of cellular responses via key cytoplasmic… (More)
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Highly Cited
1999
Highly Cited
1999
Activation of NF-kappaB by RANK requires tumor necrosis factor receptor-associated factor (TRAF) 6 and NF-kappaB-inducing kinase. Identification of a novel TRAF6 interaction motif.
Various members of the tumor necrosis factor (TNF) receptor superfamily activate nuclear factor kappaB (NF-kappaB) and the c-Jun… (More)
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Highly Cited
1998
Highly Cited
1998
ASK1 is essential for JNK/SAPK activation by TRAF2.
Tumor necrosis factor (TNF)-induced activation of the c-jun N-terminal kinase (JNK, also known as SAPK; stress-activated protein… (More)
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Highly Cited
1997
Highly Cited
1997
Herpesvirus entry mediator, a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and activates the transcription factors NF-kappaB…
The mammalian tumor necrosis factor receptor (TNFR) family consists of 10 cell-surface proteins that regulate development and… (More)
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Highly Cited
1996
Highly Cited
1996
Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region.
CD40 signalings play crucial roles in B-cell function. To identify molecules which transduce CD40 signalings, we have utilized… (More)
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