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TLR6 gene

Known as: toll like receptor 6, Toll-Like Receptor 6 Gene, TLR6 
This gene is involved in immune responses through nuclear factor kappa-B signal transduction.
National Institutes of Health

Related topics

Related topics

6 relations
Antimicrobial EffectImmune responseLigand BindingReceptor Signaling

Papers overview

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Highly Cited
2017
Highly Cited
2017
Lactobacillus reuteri I5007 Modulates Intestinal Host Defense Peptide Expression in the Model of IPEC-J2 Cells and Neonatal Piglets
Modulation of the synthesis of endogenous host defense peptides (HDPs) by probiotics represents a novel antimicrobial approach… 
Highly Cited
2015
Highly Cited
2015
Activation of TLR2 and TLR6 by Dengue NS1 Protein and Its Implications in the Immunopathogenesis of Dengue Virus Infection
Dengue virus (DV) infection is the most prevalent mosquito-borne viral disease and its manifestation has been shown to be… 
Highly Cited
2015
Highly Cited
2015
HIV-1 Structural Proteins Serve as PAMPs for TLR2 Heterodimers Significantly Increasing Infection and Innate Immune Activation
Immune activation is critical to HIV infection and pathogenesis; however, our understanding of HIV innate immune activation… 
Highly Cited
2010
Highly Cited
2010
Lipid droplet formation in leprosy: Toll‐like receptor‐regulated organelles involved in eicosanoid formation and Mycobacterium leprae pathogenesis
A hallmark of LL is the accumulation of Virchow's foamy macrophages. However, the origin and nature of these lipids, as well as… 
Highly Cited
2010
Highly Cited
2010
Identification of Novel Synthetic Toll-like Receptor 2 Agonists by High Throughput Screening*
Toll-like receptors (TLRs) play a central role in host defense by inducing inflammatory and adaptive immune responses following… 
Highly Cited
2009
Highly Cited
2009
TLR–Dependent Control of Francisella tularensis Infection and Host Inflammatory Responses
Background Francisella tularensis is the causative agent of tularemia and is classified as a Category A select agent. Recent… 
Highly Cited
2008
Highly Cited
2008
Toll-like receptor 6 drives differentiation of tolerogenic dendritic cells and contributes to LcrV-mediated plague pathogenesis.
Highly Cited
2008
Highly Cited
2008
Identification of Francisella tularensis Lipoproteins That Stimulate the Toll-like Receptor (TLR) 2/TLR1 Heterodimer*
The innate immune response to Francisella tularensis is primarily mediated by TLR2, though the bacterial products that stimulate… 
Highly Cited
2006
Highly Cited
2006
Differential interactions of fimbriae and lipopolysaccharide from Porphyromonas gingivalis with the Toll‐like receptor 2‐centred pattern recognition apparatus
The lipopolysaccharide (LPS) and fimbriae of Porphyromonas gingivalis play important roles in periodontal inflammation and… 
Highly Cited
2005
Highly Cited
2005
Surface-Expressed TLR6 Participates in the Recognition of Diacylated Lipopeptide and Peptidoglycan in Human Cells1
Recognition of microbial components by TLR2 requires cooperation with other TLRs. TLR6 has been shown to be required for the… 
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