TLR4 wt Allele

Known as: Toll-Like Receptor 4 wt Allele, Homolog of Drosophila Toll Gene, TOLL, Drosophila, Homolog of Gene 
Human TLR4 wild-type allele is located within 9q32-q33 and is approximately 11 kb in length. This allele, which encodes toll-like receptor 4 protein… (More)
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
The NLRP3 inflammasome is a key component of the innate immune response to pathogenic infection and tissue damage. It is also… (More)
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Highly Cited
2008
Highly Cited
2008
The beta-glucan receptor dectin-1 and Toll-like receptors TLR2 and TLR4 are the main receptors for recognition of Candida… (More)
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Highly Cited
2007
Highly Cited
2007
Dying cells stimulate inflammation, and this response is thought to contribute to the pathogenesis of many diseases. Very little… (More)
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Highly Cited
2006
Highly Cited
2006
TLR4 is the receptor for LPS and plays a critical role in innate immunity. Stimulation of TLR4 activates proinflammatory pathways… (More)
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Review
2002
Review
2002
Bacterial lipopolysaccharides (LPS) typically consist of a hydrophobic domain known as lipid A (or endotoxin), a nonrepeating… (More)
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Highly Cited
2002
Highly Cited
2002
Recent studies have initiated a paradigm shift in the understanding of the function of heat shock proteins (HSP). It is now clear… (More)
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Highly Cited
2002
Highly Cited
2002
The immediate or innate immune response is the first line of defense against diverse microbial pathogens and requires the… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Inflammation is implicated in atherogenesis and plaque disruption. Toll-like receptor 2 (TLR-2) and TLR-4, a human… (More)
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Highly Cited
2000
Highly Cited
2000
Initiation and perpetuation of the inflammatory intestinal responses in inflammatory bowel disease (IBD) may result from an… (More)
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Highly Cited
1999
Highly Cited
1999
Toll-like receptor (TLR) 2 and TLR4 are implicated in the recognition of various bacterial cell wall components, such as… (More)
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