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TLR4 wt Allele

Known as: Toll-Like Receptor 4 wt Allele, Homolog of Drosophila Toll Gene, TOLL, Drosophila, Homolog of Gene 
Human TLR4 wild-type allele is located within 9q32-q33 and is approximately 11 kb in length. This allele, which encodes toll-like receptor 4 protein… 
National Institutes of Health

Related topics

Related topics

12 relations
9q32-q33Beta-Catenin Accumulation PathwayDendritic Cell PathwayImmune response

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Pancreatic cancer derived exosomes regulate the expression of TLR4 in dendritic cells via miR-203.
Highly Cited
2012
Highly Cited
2012
Histones from dying renal cells aggravate kidney injury via TLR2 and TLR4.
In AKI, dying renal cells release intracellular molecules that stimulate immune cells to secrete proinflammatory cytokines, which… 
Highly Cited
2008
Highly Cited
2008
Dectin‐1 synergizes with TLR2 and TLR4 for cytokine production in human primary monocytes and macrophages
The β‐glucan receptor dectin‐1 and Toll‐like receptors TLR2 and TLR4 are the main receptors for recognition of Candida albicans… 
Review
2007
Review
2007
Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists
The identification of the antigen recognition receptors for innate immunity, most notably the Toll-like receptors, has sparked… 
Review
2004
Review
2004
Taking a Toll on human disease: Toll-like receptor 4 agonists as vaccine adjuvants and monotherapeutic agents
Toll-like receptor (TLR) agonists are being developed for use as vaccine adjuvants and as stand-alone immunomodulators because of… 
Highly Cited
2004
Highly Cited
2004
Expression of functional toll-like receptor-2 and -4 on alveolar epithelial cells.
The recognition of potentially harmful microorganisms involves the specific recognition of pathogen-associated molecular patterns… 
Highly Cited
2004
Highly Cited
2004
IL-10 Released by Concomitant TLR2 Stimulation Blocks the Induction of a Subset of Th1 Cytokines That Are Specifically Induced by TLR4 or TLR3 in Human Dendritic Cells1
Recognition of microbial products through TLRs triggers the expression of several cytokines that regulate innate and adaptive… 
Highly Cited
2003
Highly Cited
2003
Minimally Modified LDL Binds to CD14, Induces Macrophage Spreading via TLR4/MD-2, and Inhibits Phagocytosis of Apoptotic Cells*
Minimally modified low density lipoprotein (mmLDL) is a pro-inflammatory and pro-atherogenic lipoprotein that, unlike profoundly… 
Highly Cited
2003
Highly Cited
2003
Toll‐like receptor 2 (TLR2) and TLR4 differentially activate human mast cells
In the present report we have analyzed whether human normal cord blood‐derived mast cells (CBMC) could interact with bacterial… 
Highly Cited
2002
Highly Cited
2002
Involvement of Toll-like Receptor (TLR) 2 and TLR4 in Cell Activation by Mannuronic Acid Polymers*
The alginate capsule produced by the human pathogen Pseudomonas aeruginosa is composed mainly of mannuronic acid polymers (poly-M… 
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