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Identification of DC-SIGN, a Novel Dendritic Cell–Specific ICAM-3 Receptor that Supports Primary Immune Responses
Contact between dendritic cells (DC) and resting T cells is essential to initiate a primary immune response. Here, we demonstrate that ICAM-3 expressed by resting T cells is important in this firstExpand
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Toll-like receptor 2 controls expansion and function of regulatory T cells.
Tregs play a central role in the suppression of immune reactions and prevention of autoimmune responses harmful to the host. During acute infection, however, Tregs might hinder effector T cellExpand
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Different Faces of the Heme-Heme Oxygenase System in Inflammation
The heme-heme oxygenase system has recently been recognized to possess important regulatory properties. It is tightly involved in both physiological as well as pathophysiological processes, such asExpand
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The immunosuppressive tumour network: myeloid‐derived suppressor cells, regulatory T cells and natural killer T cells
Myeloid‐derived suppressor cells (MDSC) and regulatory T (Treg) cells are major components of the immune suppressive tumour microenvironment (TME). Both cell types expand systematically inExpand
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A dendritic-cell-derived C–C chemokine that preferentially attracts naive T cells
Dendritic cells form a system of highly efficient antigen-presenting cells. After capturing antigen in the periphery, they migrate to lymphoid organs where they present the antigen to T cells,. TheirExpand
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LAIR-1, a novel inhibitory receptor expressed on human mononuclear leukocytes.
In the present study, we describe a novel inhibitory receptor, leukocyte-associated immunoglobulin-like receptor-1 (LAIR-1), that is constitutively expressed on the majority of human peripheral bloodExpand
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Human dectin-1 deficiency and mucocutaneous fungal infections.
Mucocutaneous fungal infections are typically found in patients who have no known immune defects. We describe a family in which four women who were affected by either recurrent vulvovaginalExpand
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Magnetic resonance tracking of dendritic cells in melanoma patients for monitoring of cellular therapy
The success of cellular therapies will depend in part on accurate delivery of cells to target organs. In dendritic cell therapy, in particular, delivery and subsequent migration of cells to regionalExpand
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NOD2 and Toll-Like Receptors Are Nonredundant Recognition Systems of Mycobacterium tuberculosis
Infection with Mycobacterium tuberculosis is one of the leading causes of death worldwide. Recognition of M. tuberculosis by pattern recognition receptors is crucial for activation of both innate andExpand
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Dectin‐1 synergizes with TLR2 and TLR4 for cytokine production in human primary monocytes and macrophages
The β‐glucan receptor dectin‐1 and Toll‐like receptors TLR2 and TLR4 are the main receptors for recognition of Candida albicans by the innate immune system. It has been reported that dectin‐1Expand
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