TLR3 wt Allele

Known as: CD283, Toll-Like Receptor 3 wt Allele, TLR3 
Human TLR3 wild-type allele is located within 4q35 and is approximately 16 kb in length. This allele, which encodes toll-like receptor 3 protein… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
Endosomal TLRs play an important role in innate immune response as well as in autoimmune processes. In the therapy of systemic… (More)
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Highly Cited
2011
Highly Cited
2011
Autosomal dominant TLR3 deficiency has been identified as a genetic etiology of childhood herpes simplex virus 1 (HSV-1… (More)
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Highly Cited
2010
Highly Cited
2010
The relative roles of the endosomal TLR3/7/8 versus the intracellular RNA helicases RIG-I and MDA5 in viral infection is much… (More)
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Highly Cited
2008
Highly Cited
2008
Ligands from dying cells are a source of Toll-like receptor (TLR) activating agents. Although TLR3 is known to respond to RNA… (More)
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Highly Cited
2007
Highly Cited
2007
Respiratory syncytial virus (RSV) is one of the most common viral pathogens causing severe lower respiratory tract infections in… (More)
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Highly Cited
2006
Highly Cited
2006
Toll-like receptors (TLRs) are innate immunity receptors that are expressed on a wide range of cell types, including CNS glial… (More)
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Highly Cited
2006
Highly Cited
2006
The liver is known to be a classical immunoprivileged site with a relatively high resistance against immune responses. Here we… (More)
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Highly Cited
2005
Highly Cited
2005
Toll-like receptors (TLRs) sense microbial products and initiate adaptive immune responses by activating dendritic cells (DCs… (More)
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Highly Cited
2005
Highly Cited
2005
TLRs play a critical role in early innate immune response to virus infection. TLR3 together with TLR7 and TLR8 constitute a… (More)
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Review
2002
Review
2002
The mammalian Toll-like receptors (TLRs) are expressed on macrophages and dendritic cells, which are primarily involved in innate… (More)
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