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TLN1 gene

Known as: TALIN 1, TLN1, TALIN 
 
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Talin has emerged as the key cytoplasmic protein that mediates integrin adhesion to the extracellular matrix. In this Review, we… Expand
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Review
2016
Review
2016
Integrin adhesion receptors mediate the adhesion of blood cells, such as leukocytes, to other cells, such as endothelial cells… Expand
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Highly Cited
2016
Highly Cited
2016
Cell function depends on tissue rigidity, which cells probe by applying and transmitting forces to their extracellular matrix… Expand
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Highly Cited
2007
Highly Cited
2007
Focal adhesions (FAs) regulate cell migration. Vinculin, with its many potential binding partners, can interconnect signals in… Expand
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Highly Cited
2003
Highly Cited
2003
Control of integrin affinity for ligands (integrin activation) is essential for normal cell adhesion, migration, and assembly of… Expand
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Highly Cited
2002
Highly Cited
2002
Membrane phosphoinositides control a variety of cellular processes through the recruitment and/or regulation of cytosolic… Expand
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Highly Cited
2002
Highly Cited
2002
Cellular regulation of the ligand binding affinity of integrin adhesion receptors (integrin activation) depends on the integrin… Expand
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Highly Cited
1998
Highly Cited
1998
The C-terminus of mouse talin (amino acids 2345-2541) is responsible for all of the protein's f-actin binding capacity. Unlike… Expand
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Highly Cited
1992
Highly Cited
1992
We have recently shown that changes in tyrosine phosphorylation of a 130-kDa protein(s) (pp130) may be involved in integrin… Expand
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Highly Cited
1986
Highly Cited
1986
Many observations suggest the presence of transmembrane linkages between the cytoskeleton and the extracellular matrix. In… Expand
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