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Talin

Known as: Band 2 Protein, Protein, Band 2, Talin [Chemical/Ingredient] 
A 235-kDa cytoplasmic protein that is also found in platelets. It has been localized to regions of cell-substrate adhesion. It binds to INTEGRINS… Expand
National Institutes of Health

Papers overview

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Review
2013
Review
2013
Integrin receptors provide a dynamic, tightly-regulated link between the extracellular matrix (or cellular counter-receptors) and… Expand
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Highly Cited
2009
Highly Cited
2009
The molecular mechanism by which a mechanical stimulus is translated into a chemical response in biological systems is still… Expand
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Highly Cited
2009
Highly Cited
2009
A key molecular link between cells and the extracellular matrix is the binding between fibronectin and integrins α5β1 and αvβ3… Expand
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Highly Cited
2006
Highly Cited
2006
The ability of adhesion receptors to transmit biochemical signals and mechanical force across cell membranes depends on… Expand
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Highly Cited
2004
Highly Cited
2004
Dynamic regulation of adhesion complexes is required for cell migration and has therefore emerged as a key issue in the study of… Expand
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Highly Cited
2003
Highly Cited
2003
The binding of cytoplasmic proteins, such as talin, to the cytoplasmic domains of integrin adhesion receptors mediates… Expand
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Highly Cited
2003
Highly Cited
2003
Mechanical forces on matrix–integrin–cytoskeleton linkages are crucial for cell viability, morphology and organ function. The… Expand
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Highly Cited
2001
Highly Cited
2001
Talin is a structural component of focal adhesion sites and is thought to be engaged in multiple protein interactions at the… Expand
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Highly Cited
1999
Highly Cited
1999
The β subunit cytoplasmic domains of integrin adhesion receptors are necessary for the connection of these receptors to the actin… Expand
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Highly Cited
1984
Highly Cited
1984
In cultured fibroblasts, microfilament bundles terminate at adhesion plaques (focal contacts), the specialized regions where the… Expand
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