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Talin

Known as: Band 2 Protein, Protein, Band 2, Talin [Chemical/Ingredient] 
A 235-kDa cytoplasmic protein that is also found in platelets. It has been localized to regions of cell-substrate adhesion. It binds to INTEGRINS… 
National Institutes of Health

Related topics

Related topics

12 relations
Actin-Binding ProteinIn BloodProcess of secretionTLN1 gene

Narrower (2)

Platelet Protein p235talin protein, mouse

Papers overview

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2013
2013
The N terminus of SKAP55 enables T cell adhesion to TCR and integrin ligands via distinct mechanisms
In addition to promoting integrin activation at the immunological synapse, SKAP55 links T cell antigen receptor-associated… 
2009
2009
Control of High Affinity Interactions in the Talin C Terminus
In cell-extracellular matrix junctions (focal adhesions), the cytoskeletal protein talin is central to the connection of… 
Highly Cited
2000
Highly Cited
2000
Molecular mechanisms of improved adhesion and growth of an endothelial cell line cultured on polystyrene implanted with fluorine ions.
1995
1995
Down regulation of talin alters cell adhesion and the processing of the α5β1 integrin
The role of talin was addressed by down regulating its expression using an antisense RNA strategy. HeLa cells were transfected… 
1995
1995
Intracellular processing of talin occurs within focal adhesions.
CHO cells spread out on fibronectin-coated plastic were perforated with the bacterial toxin alveolysin. This treatment preserves… 
1990
1990
Dystrophin as a focal adhesion protein
Highly Cited
1989
Highly Cited
1989
The role of phosphorylation and limited proteolytic cleavage of talin and vinculin in the disruption of focal adhesion integrity.
Highly Cited
1986
Highly Cited
1986
Talin is phosphorylated on tyrosine in chicken embryo fibroblasts transformed by Rous sarcoma virus.
We have examined the extent of tyrosine phosphorylation of talin, a component of the cytoskeleton localized in the focal… 
Highly Cited
1986
Highly Cited
1986
Demonstration of a relationship between talin and P235, a major substrate of the calcium‐dependent protease in platelets
Talin is a 225,000‐Dalton protein we have purified from smooth muscle. In chick embryo fibroblasts talin is found in adhesion… 
1980
1980
Movement of calcium ions and release of histamine from rat mast cells.
Rat mast cells were stimulated for histamine release in a medium containing radioactive calcium, by band 2 protein (B2) and… 
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