Talin

Known as: Band 2 Protein, Protein, Band 2, Talin [Chemical/Ingredient] 
A 235-kDa cytoplasmic protein that is also found in platelets. It has been localized to regions of cell-substrate adhesion. It binds to INTEGRINS… (More)
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
The molecular mechanism by which a mechanical stimulus is translated into a chemical response in biological systems is still… (More)
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Highly Cited
2009
Highly Cited
2009
Cell migration is a dynamic process that requires temporal and spatial regulation of integrin activation and focal adhesion… (More)
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Highly Cited
2004
Highly Cited
2004
Dynamic regulation of adhesion complexes is required for cell migration and has therefore emerged as a key issue in the study of… (More)
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Highly Cited
2004
Highly Cited
2004
Vinculin is a conserved component and an essential regulator of both cell–cell (cadherin-mediated) and cell–matrix (integrin… (More)
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Review
2004
Review
2004
The cytoskeletal proteins talin and vinculin form part of a macromolecular complex on the cytoplasmic face of integrin-mediated… (More)
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Highly Cited
2002
Highly Cited
2002
We show that the Drosophila gene rhea, isolated because its wing blister phenotype is typical of mutants affecting integrin… (More)
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Highly Cited
1999
Highly Cited
1999
The beta subunit cytoplasmic domains of integrin adhesion receptors are necessary for the connection of these receptors to the… (More)
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Highly Cited
1995
Highly Cited
1995
The interaction of cells with extracellular matrix proteins plays a critical role in a variety of biological processes. Recent… (More)
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Highly Cited
1990
Highly Cited
1990
TALIN is a high-molecular-weight cytoskeletal protein concentrated at regions of cell–substratum contact1 and, in lymphocytes, at… (More)
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Highly Cited
1984
Highly Cited
1984
In cultured fibroblasts, microfilament bundles terminate at adhesion plaques (focal contacts), the specialized regions where the… (More)
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