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Talin

Known as: Band 2 Protein, Protein, Band 2, Talin [Chemical/Ingredient] 
A 235-kDa cytoplasmic protein that is also found in platelets. It has been localized to regions of cell-substrate adhesion. It binds to INTEGRINS… 
National Institutes of Health

Related topics

Related topics

12 relations
Actin-Binding ProteinIn BloodProcess of secretionTLN1 gene

Narrower (2)

Platelet Protein p235talin protein, mouse

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Mechanosensitive TRPC1 Channels Promote Calpain Proteolysis of Talin to Regulate Spinal Axon Outgrowth
Intracellular Ca2+ signals control the development and regeneration of spinal axons downstream of chemical guidance cues, but… 
Review
2009
Review
2009
Integrin-mediated adhesion and stem-cell-niche interactions
The regulation of stem cell behavior and maintenance typically involves the integration of both intrinsic and extrinsic cues. One… 
Highly Cited
2007
Highly Cited
2007
Rate and extent of pH decline affect proteolysis of cytoskeletal proteins and water-holding capacity in pork.
Highly Cited
2005
Highly Cited
2005
Quantitative methods for analysis of integrin binding and focal adhesion formation on biomaterial surfaces.
Highly Cited
2004
Highly Cited
2004
Myoblast migration is regulated by calpain through its involvement in cell attachment and cytoskeletal organization.
Highly Cited
2003
Highly Cited
2003
Tyrosine phosphorylation of type Iγ phosphatidylinositol phosphate kinase by Src regulates an integrin–talin switch
Engagement of integrin receptors with the extracellular matrix induces the formation of focal adhesions (FAs). Dynamic regulation… 
Highly Cited
1999
Highly Cited
1999
Degraded Collagen Fragments Promote Rapid Disassembly of Smooth Muscle Focal Adhesions That Correlates with Cleavage of Pp125FAK, Paxillin, and Talin
Active matrix metalloproteinases and degraded collagen are observed in disease states, such as atherosclerosis. To examine… 
Highly Cited
1991
Highly Cited
1991
Localization of paxillin, a focal adhesion protein, to smooth muscle dense plaques, and the myotendinous and neuromuscular junctions of skeletal muscle.
Highly Cited
1990
Highly Cited
1990
Sequence and domain structure of talin
TALIN is a high-molecular-weight cytoskeletal protein concentrated at regions of cell–substratum contact1 and, in lymphocytes, at… 
Highly Cited
1968
Highly Cited
1968
ISOLATION AND CHARACTERIZATION OF PERMEABILITY FACTORS FROM RABBIT NEUTROPHILS
Four basic proteins that increase vascular permeability have been isolated in purified form from rabbit neutrophilic granules… 
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