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THRA wt Allele

Known as: THRA2, Thyroid Hormone Receptor Alpha Gene, ERBA1 
Human THRA wild-type allele is located in the vicinity of 17q11.2 and is approximately 31 kb in length. This allele, which encodes thyroid hormone… 
National Institutes of Health

Related topics

Related topics

15 relations
17q11.2-q12Biologic DevelopmentCell Differentiation processCell Proliferation

Broader (1)

THRA gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Impaired adipogenesis caused by a mutated thyroid hormone alpha1 receptor.
Thyroid hormone (T3) is critical for growth, differentiation, and maintenance of metabolic homeostasis. Mice with a knock-in… 
2004
2004
Characteristics of 3,5,3'-triiodothyronine (T3)-uptake system of tadpole red blood cells: effect of endocrine-disrupting chemicals on cellular T3 response.
We characterized the 3,5,3'-L-triiodothyronine (T3)- uptake system on the plasma membrane of Rana catesbeiana tadpole red blood… 
Highly Cited
2003
Highly Cited
2003
A Thyroid Hormone Receptor α Gene Mutation (P398H) Is Associated with Visceral Adiposity and Impaired Catecholamine-stimulated Lipolysis in Mice*
Thyroid hormone has profound effects on metabolic homeostasis, regulating both lipogenesis and lipolysis, primarily by modulating… 
Highly Cited
2002
Highly Cited
2002
Sporadic breast cancer in young women: Prevalence of loss of heterozygosity at p53, BRCA1 and BRCA2
Previous studies have shown that breast cancers have more aggressive pathologic features in young women. In order to examine… 
Highly Cited
2001
Highly Cited
2001
Suppression of the deafness and thyroid dysfunction in Thrb-null mice by an independent mutation in the Thra thyroid hormone receptor alpha gene.
Deletion of thyroid hormone receptor beta (TR beta), a ligand-dependent transcription factor encoded by the Thrb gene, causes… 
Highly Cited
1999
Highly Cited
1999
Microsatellite DNA instability in COPD.
STUDY OBJECTIVES Cigarette smoking is the prime cause of COPD; however, only a few smokers develop the disease. In a previous… 
Highly Cited
1997
Highly Cited
1997
Application of transmission disequilibrium tests to nonsyndromic oral clefts: including candidate genes and environmental exposures in the models.
Extensive epidemiological and genetic studies of the cause of oral clefts have demonstrated strong familial aggregation but have… 
Highly Cited
1997
Highly Cited
1997
Familial multiple-system tauopathy with presenile dementia is localized to chromosome 17.
An autosomal dominant presenile dementia affecting 39 individuals in a seven-generation, 383-member pedigree has been studied at… 
Highly Cited
1993
Highly Cited
1993
THRA1 and D17S183 flank an interval of < 4 cM for the breast-ovarian cancer gene (BRCA1) on chromosome 17q21.
In order to pinpoint the locale of the gene for early-onset familial breast and ovarian cancer (BRCA1), polymorphisms were… 
1993
1993
A somatic cell hybrid map of the long arm of human chromosome 17, containing the familial breast cancer locus (BRCA1).
We describe a detailed somatic cell hybrid map of human chromosome 17q11.2-q23, containing the familial breast and ovarian cancer… 
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