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THRA wt Allele

Known as: THRA2, Thyroid Hormone Receptor Alpha Gene, ERBA1 
Human THRA wild-type allele is located in the vicinity of 17q11.2 and is approximately 31 kb in length. This allele, which encodes thyroid hormone… Expand
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Objective  Septic shock is one of various causes of nonthyroidal illness syndrome (NTIS). In humans, the molecular mechanisms… Expand
2007
2007
Thyroid hormone (T3) is critical for growth, differentiation, and maintenance of metabolic homeostasis. Mice with a knock-in… Expand
Highly Cited
2003
Highly Cited
2003
Thyroid hormone has profound effects on metabolic homeostasis, regulating both lipogenesis and lipolysis, primarily by modulating… Expand
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Highly Cited
2002
Highly Cited
2002
Previous studies have shown that breast cancers have more aggressive pathologic features in young women. In order to examine… Expand
Highly Cited
2001
Highly Cited
2001
Deletion of thyroid hormone receptor beta (TR beta), a ligand-dependent transcription factor encoded by the Thrb gene, causes… Expand
Highly Cited
1999
Highly Cited
1999
STUDY OBJECTIVES Cigarette smoking is the prime cause of COPD; however, only a few smokers develop the disease. In a previous… Expand
Highly Cited
1997
Highly Cited
1997
Extensive epidemiological and genetic studies of the cause of oral clefts have demonstrated strong familial aggregation but have… Expand
Highly Cited
1997
Highly Cited
1997
An autosomal dominant presenile dementia affecting 39 individuals in a seven-generation, 383-member pedigree has been studied at… Expand
Highly Cited
1993
Highly Cited
1993
In order to pinpoint the locale of the gene for early-onset familial breast and ovarian cancer (BRCA1), polymorphisms were… Expand
Highly Cited
1992
Highly Cited
1992
Analyses of losses of heterozygosity and linkage studies have implicated a gene(s) on chromosome 17q in the genesis of sporadic… Expand
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