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TERT gene

Known as: TELOMERASE CATALYTIC SUBUNIT, Telomerase Reverse Transcriptase Gene, TELOMERASE REVERSE TRANSCRIPTASE 
This gene is involved in cell cycle regulation and telomere maintenance.
National Institutes of Health

Related topics

Related topics

7 relations
Cell Cycle ControlNeuroblastomaTERT protein, humanTelomerase

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TERT wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Molecular classification of gliomas.
Highly Cited
2006
Highly Cited
2006
Synthesis and structural characterization of endohedral pyrrolidinodimetallofullerene: La2@C80(CH2)2NTrt.
The endohedral pyrrolidinodimetallofullerene, La2@C80(CH2)2NTrt (Trt = triphenylmethyl), was successfully synthesized and… 
Highly Cited
2005
Highly Cited
2005
Survivin enhances telomerase activity via up-regulation of specificity protein 1- and c-Myc-mediated human telomerase reverse transcriptase gene transcription.
Highly Cited
2005
Highly Cited
2005
Two Purified Domains of Telomerase Reverse Transcriptase Reconstitute Sequence-specific Interactions with RNA*
Telomerase reverse transcriptase (TERT) and telomerase RNA (TER) function together to create a uniquely specialized polymerase… 
Highly Cited
2005
Highly Cited
2005
A human beta-cell line for transplantation therapy to control type 1 diabetes.
A human pancreatic beta-cell line that is functionally equivalent to primary beta-cells has not been available. We established a… 
Highly Cited
2004
Highly Cited
2004
Immunization of Patients with the hTERT:540-548 Peptide Induces Peptide-Reactive T Lymphocytes That Do Not Recognize Tumors Endogenously Expressing Telomerase
Purpose: Telomerase is an attractive target antigen for cancer immunotherapies because it is expressed in >85% of human tumors… 
Highly Cited
2002
Highly Cited
2002
Targeted expression of green fluorescent protein/tumor necrosis factor-related apoptosis-inducing ligand fusion protein from human telomerase reverse transcriptase promoter elicits antitumor activity…
Liver toxicity is the major concern for use of recombinant human tumor necrosis factor-related apoptosis-inducing ligand (TRAIL… 
Highly Cited
2000
Highly Cited
2000
Template definition by Tetrahymena telomerase reverse transcriptase
The ribonucleoprotein enzyme telomerase extends chromosome ends by copying a specific template sequence within its integral RNA… 
Highly Cited
2000
Highly Cited
2000
A novel functional genomics approach identifies mTERT as a suppressor of fibroblast transformation
As a tool for functional genomics, a hairpin ribozyme gene library with randomized target recognition sequences was constructed… 
Highly Cited
1999
Highly Cited
1999
Telomerase activity and human telomerase reverse transcriptase mRNA expression in soft tissue tumors: correlation with grade, histology, and proliferative activity.
Telomerase activity (TA) is detected in most human cancers but, with few exceptions, not in normal somatic cells. Little is known… 
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