TERT wt Allele

Known as: Telomerase Reverse Transcriptase wt Allele, EST2, TCS1 
Human TERT wild-type allele is located in the vicinity of 5p15.33 and is approximately 42 kb in length. This allele, which encodes telomerase reverse… (More)
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
BACKGROUND The prediction of clinical behavior, response to therapy, and outcome of infiltrative glioma is challenging. On the… (More)
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Highly Cited
2013
Highly Cited
2013
Reactivation of telomerase has been implicated in human tumorigenesis, but the underlying mechanisms remain poorly understood… (More)
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Highly Cited
2009
Highly Cited
2009
The common sequence variants that have recently been associated with cancer risk are particular to a single cancer type or at… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Idiopathic pulmonary fibrosis is progressive and often fatal; causes of familial clustering of the disease are unknown… (More)
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Highly Cited
2007
Highly Cited
2007
Significant improvement in the understanding of mesenchymal stem cell (MSC) biology has opened the way to their clinical use… (More)
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Highly Cited
2004
Highly Cited
2004
By expressing two genes (hTERT and Cdk4), we have developed a method to reproducibly generate continuously replicating human… (More)
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Highly Cited
2003
Highly Cited
2003
In normal human cells, telomeres shorten with successive rounds of cell division, and immortalization correlates with… (More)
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Highly Cited
2000
Highly Cited
2000
Normal human cells exhibit a limited replicative life span in culture, eventually arresting growth by a process termed senescence… (More)
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Highly Cited
1998
Highly Cited
1998
Normal somatic cells have a finite life span [1] and lose telomeric DNA, present at the ends of chromosomes, each time they… (More)
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Highly Cited
1997
Highly Cited
1997
The maintenance of chromosome termini, or telomeres, requires the action of the enzyme telomerase, as conventional DNA poly… (More)
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