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Telomerase
Known as:
Telomerase Reverse Transcriptase
, Reverse Transcriptase, Telomerase
, Telomerase [Chemical/Ingredient]
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An enzyme in cells that helps keep them alive by adding DNA to telomeres (the ends of chromosomes). Each time a cell divides, the telomeres lose a…
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National Institutes of Health
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Related topics
Related topics
28 relations
Cell Nucleus
Enzyme Gene
In Blood
Neuroblastoma
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Broader (2)
DNA Nucleotidylexotransferase
nucleotidyltransferase
Narrower (7)
TERT protein, Arabidopsis
TERT protein, human
Telomerase Catalytic Subunit
Tert protein, mouse
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Eimeria tenella: 14-3-3 protein interacts with telomerase
Na Zhao
,
P. Gong
,
+6 authors
Xi-chen Zhang
Parasitology Research
2014
Corpus ID: 18476427
Telomerase, consisting of telomerase RNA and telomerase reverse transcriptase (TERT), is responsible for the maintenance of the…
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2013
2013
Stem cell therapeutics for cancer
K. Shah
2013
Corpus ID: 68595390
Contributors vii Preface xi Section 1 Introduction 1 1 Stem Cell Sources and Their Potential for Cancer Therapeutics 3 Khalid…
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2013
2013
Characterization of Cholesterol Homeostasis in Telomerase-immortalized Tangier Disease Fibroblasts Reveals Marked Phenotype Variability*
F. Kannenberg
,
K. Gorzelniak
,
+6 authors
Michael Walter
Journal of Biological Chemistry
2013
Corpus ID: 205334651
Background: The reason for the variability in degree of atherosclerosis in Tangier disease remains poorly understood. Results…
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2006
2006
Telomerase Activation in Human Hepatocarcinogenesis
P. Hytiroglou
,
N. Theise
American Journal of Gastroenterology
2006
Corpus ID: 19412703
Active telomerase is present in the majority of malignant human tumors, including most cases of hepatocellular carcinoma (HCC…
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2006
2006
Dynamic alteration of telomerase expression and its diagnostic significance in liver or peripheral blood for hepatocellular carcinoma.
D. Yao
,
Wei Wu
,
+6 authors
Xian-yong Meng
World Journal of Gastroenterology
2006
Corpus ID: 30923282
AIM To investigate the dynamic alteration of telomerase expression during development of hepatocellular carcinoma (HCC) and its…
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Review
2006
Review
2006
8 Telomerase-independent Telomere Maintenance in Yeast
M. McEachern
,
J. Haber
2006
Corpus ID: 89086447
Prior to identification of telomerase, recombination was considered a possible mechanism for telomere maintenance (see Chapter 1…
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Review
2004
Review
2004
V. N. Anisimov, Molekulyarnye i fiziologicheskie mekhanizmy stareniya(Molecular and Physiological Mechanisms of Aging), St. Petersburg: Nauka, 2003, 468 pp. [in Russian]
V. Anisimov
Human Physiology
2004
Corpus ID: 34281945
The increased proportion of elderly persons in the global population and the unprecedented growth of life expectancy during the…
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2002
2002
Telomerase inhibition and telomere loss in BEL-7404 human hepatoma cells treated with doxorubicin.
Ru-gang Zhang
,
Li-Xia Guo
,
Xing-wang Wang
,
Hong Xie
World Journal of Gastroenterology
2002
Corpus ID: 28627808
AIM To study the effects of doxorubicin on telomerase activity and telomere length in hepatocellular carcinoma. METHODS…
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2000
2000
Development of a condemned mucosa syndrome and pathogenesis of human papillomavirus-associated upper aerodigestive tract and uterine cervical tumors.
M. Pillai
,
M. Nair
Experimental and molecular pathology (Print)
2000
Corpus ID: 36076119
High-risk human papillomaviruses (HPVs) have been shown to be involved in the pathogenesis of many squamous carcinomas…
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1998
1998
Flexible Positioning of the Telomerase-Associated Nuclease Leads to Preferential Elimination of Nontelomeric DNA
E. Greene
,
J. Bednenko
,
D. Shippen
Molecular and Cellular Biology
1998
Corpus ID: 5635318
ABSTRACT In addition to a reverse transcriptase activity, telomerase is associated with a DNA endonuclease that removes…
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