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Telomerase

Known as: Telomerase Reverse Transcriptase, Reverse Transcriptase, Telomerase, Telomerase [Chemical/Ingredient] 
An enzyme in cells that helps keep them alive by adding DNA to telomeres (the ends of chromosomes). Each time a cell divides, the telomeres lose a… 
National Institutes of Health

Related topics

Related topics

28 relations
Cell NucleusEnzyme GeneIn BloodNeuroblastoma

Broader (2)

DNA Nucleotidylexotransferasenucleotidyltransferase

Narrower (7)

TERT protein, ArabidopsisTERT protein, humanTelomerase Catalytic SubunitTert protein, mouse

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Blood vessels engineered from human cells
Review
2002
Review
2002
Molecular changes accompanying senescence and immortalization of cultured human mammary epithelial cells.
Review
2002
Review
2002
Telomerase inhibition, oligonucleotides, and clinical trials
Telomerase is expressed in most types of tumors but not in most somatic cells. This observation has led to two hypotheses; (i… 
Highly Cited
2001
Highly Cited
2001
BJ fibroblasts display high antioxidant capacity and slow telomere shortening independent of hTERT transfection.
Review
2000
Review
2000
Repair of telomeric DNA prior to replicative senescence
Highly Cited
2000
Highly Cited
2000
Molecular definition of a small amplification domain within 3q26 in tumors of cervix, ovary, and lung.
Highly Cited
2000
Highly Cited
2000
Telomerase in alveolar epithelial development and repair.
Telomerase expression and activity were examined in the developing lung and in the adult lung during repair after injury. Both… 
Highly Cited
1997
Highly Cited
1997
The anchor site of telomerase from Euplotes aediculatus revealed by photo-cross-linking to single- and double-stranded DNA primers
Telomerase is a ribonucleoprotein enzyme that adds telomeric sequence repeats to the ends of linear chromosomes. In vitro… 
Review
1996
Review
1996
Involvement of telomeric sequences in chromosomal aberrations.
Highly Cited
1993
Highly Cited
1993
Tetrahymena telomerase catalyzes nucleolytic cleavage and nonprocessive elongation.
Telomerase is a ribonucleoprotein enzyme that adds telomeric repeats to chromosomes, maintaining telomere length and stabilizing… 
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