Telomerase

Known as: Telomerase Reverse Transcriptase, Reverse Transcriptase, Telomerase, Telomerase [Chemical/Ingredient] 
An enzyme in cells that helps keep them alive by adding DNA to telomeres (the ends of chromosomes). Each time a cell divides, the telomeres lose a… (More)
National Institutes of Health

Papers overview

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Review
2008
Review
2008
Telomerase is an attractive cancer target as it appears to be required in essentially all tumours for immortalization of a subset… (More)
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Highly Cited
2007
Highly Cited
2007
Successful reprogramming of differentiated human somatic cells into a pluripotent state would allow creation of patient- and… (More)
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Highly Cited
2007
Highly Cited
2007
BACKGROUND Idiopathic pulmonary fibrosis is progressive and often fatal; causes of familial clustering of the disease are unknown… (More)
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Highly Cited
2006
Highly Cited
2006
To direct human embryonic stem (HES) cells to a dopaminergic neuronal fate, we cocultured HES cells that were exposed to both… (More)
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Review
2005
Review
2005
The molecular features of telomeres and telomerase are conserved among most eukaryotes. How telomerase and telomeres function and… (More)
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Highly Cited
1999
Highly Cited
1999
Telomere maintenance is thought to play a role in signaling cellular senescence; however, a link with organismal aging processes… (More)
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Highly Cited
1999
Highly Cited
1999
The ectopic expression of telomerase in normal human cells results in an extended lifespan, indicating that telomere shortening… (More)
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Highly Cited
1998
Highly Cited
1998
Normal human cells undergo a finite number of cell divisions and ultimately enter a nondividing state called replicative… (More)
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Highly Cited
1997
Highly Cited
1997
Telomerase, the ribonucleoprotein enzyme that elongates telomeres, is repressed in normal human somatic cells but is reactivated… (More)
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Highly Cited
1997
Highly Cited
1997
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Telomerase RNA… (More)
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