DNA Nucleotidylexotransferase

Known as: Terminal Addition Enzyme, Terminal deoxyribonucleotidyl transferase, Deoxynucleotidyl Transferase 
A non-template-directed DNA polymerase normally found in vertebrate thymus and bone marrow. It catalyzes the elongation of oligo- or… (More)
National Institutes of Health

Related topics

Related topics

15 relations
Cells.terminal deoxyribonucleotidyl transferase:PrThr:Pt:Body fld:OrdDNA nucleotidylexotransferase activityDNTT geneDNTT wt Allele
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DNA Nucleotidylexotransferase, humanTelomerase

Papers overview

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Highly Cited
2008
Highly Cited
2008
Dicer Ablation Affects Antibody Diversity and Cell Survival in the B Lymphocyte Lineage
To explore the role of Dicer-dependent control mechanisms in B lymphocyte development, we ablated this enzyme in early B cell… (More)
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Highly Cited
2007
Highly Cited
2007
Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn's disease.
BACKGROUND Epithelial barrier function is impaired in Crohn's disease. AIM To define the underlying cellular mechanisms with… (More)
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Highly Cited
2006
Highly Cited
2006
Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5.
Angiogenesis and signaling through the RAF/mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase (MEK)/ERK… (More)
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Highly Cited
2002
Highly Cited
2002
Partial peripheral nerve injury promotes a selective loss of GABAergic inhibition in the superficial dorsal horn of the spinal cord.
To clarify whether inhibitory transmission in the superficial dorsal horn of the spinal cord is reduced after peripheral nerve… (More)
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Review
2002
Review
2002
Origins and functions of B-1 cells with notes on the role of CD5.
Whether B-1a (CD5+) cells are a distinct lineage derived from committed fetal/neonatal precursors or arise from follicular B-2… (More)
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Highly Cited
2001
Highly Cited
2001
Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress.
Erythropoietin (EPO) promotes neuronal survival after hypoxia and other metabolic insults by largely unknown mechanisms… (More)
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Highly Cited
1998
Highly Cited
1998
Activation and cleavage of caspase-3 in apoptosis induced by experimental cerebral ischemia.
We examined the expression, activation, and cellular localization of caspase-3 (CPP32) using immunohistochemistry, immunoblots… (More)
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Highly Cited
1997
Highly Cited
1997
Neuronal and glial apoptosis after traumatic spinal cord injury.
Cell death was examined by studying the spinal cords of rats subjected to traumatic insults of mild to moderate severity. Within… (More)
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Highly Cited
1996
Highly Cited
1996
Apoptotic and necrotic myocyte cell deaths are independent contributing variables of infarct size in rats.
Programmed cell death in the myocardium has been linked to ischemia reperfusion injury as well as to excessive mechanical forces… (More)
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Highly Cited
1993
Highly Cited
1993
Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays.
DNA strand breaks which occur in HL-60 cells as a result of activation of endonuclease during apoptosis induced by cell treatment… (More)
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