FAQ

DNA nucleotidylexotransferase activity

Known as: terminal deoxyribonucleotidyltransferase activity, terminal deoxynucleotidyltransferase activity, deoxynucleotidyl terminal transferase activity 
Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). [EC:2.7.7.31]
National Institutes of Health

Topic mentions per year

Topic mentions per year

1973-2018
05101519732018

Related topics

Related topics

6 relations
DNA NucleotidylexotransferaseDNA Nucleotidylexotransferase, humanDNTT wt Allelenegative regulation of DNA nucleotidylexotransferase activity
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Broader (1)

DNTT gene

Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
DNA nucleotidylexotransferase activity
DNA Nucleotidylexotransferase
negative regulation of DNA nucleotidylexotransferase activity
positive regulation of DNA nucleotidylexotransferase activity
DNA Nucleotidylexotransferase, human
DNTT gene

Papers overview

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Highly Cited
2000
Highly Cited
2000
De novo initiation of RNA synthesis by the RNA-dependent RNA polymerase (NS5B) of hepatitis C virus.
Hepatitis C virus (HCV) NS5B protein possesses an RNA-dependent RNA polymerase (RdRp) activity, a major function responsible for… (More)
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1999
1999
Molecular mechanisms and selection influence the generation of the human V lambda J lambda repertoire.
To define the lambda light chain repertoire in humans, a single-cell PCR technique using genomic DNA obtained from individual… (More)
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Highly Cited
1998
Highly Cited
1998
RNA-dependent RNA polymerase activity of the soluble recombinant hepatitis C virus NS5B protein truncated at the C-terminal region.
The hepatitis C virus (HCV) NS5B protein encodes an RNA-dependent RNA polymerase (RdRP), which is the central catalytic enzyme of… (More)
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Highly Cited
1997
Highly Cited
1997
Human immunodeficiency virus type 1 preintegration complexes: studies of organization and composition.
We have investigated the organization and function of human immunodeficiency virus type 1 (HIV-1) preintegration complexes (PICs… (More)
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Highly Cited
1997
Highly Cited
1997
Biochemical properties of hepatitis C virus NS5B RNA-dependent RNA polymerase and identification of amino acid sequence motifs essential for enzymatic activity.
The NS5B protein of the hepatitis C virus (HCV) is an RNA-dependent RNA polymerase (RdRp) (S.-E. Behrens, L. Tomei, and R. De… (More)
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1993
1993
RNA-directed RNA polymerase from tomato leaves. I. Purification and physical properties.
An RNA-directed RNA polymerase (RdRP, EC 2.7.7.48) from tomato leaf tissue was purified to electrophoretic homogeneity. A… (More)
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Highly Cited
1991
Highly Cited
1991
Construction of T-vectors, a rapid and general system for direct cloning of unmodified PCR products.
Although the polymerase chain reaction (1,2) (PCR) can be used to produce a large amount of a specific DNA from a complex source… (More)
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1988
1988
Lymphoid V(D)J recombination: nucleotide insertion at signal joints as well as coding joints.
The coding regions of antigen receptor genes assembled by variable-diversity-joining region [V(D)J] recombination are known in… (More)
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Highly Cited
1985
Highly Cited
1985
Identification of a specific telomere terminal transferase activity in Tetrahymena extracts.
We have found a novel activity in Tetrahymena cell free extracts that adds tandem TTGGGG repeats onto synthetic telomere primers… (More)
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Highly Cited
1978
Highly Cited
1978
Terminal transferase as a predictor of initial responsiveness to vincristine and prednisone in blastic chronic myelogenous leukemia: a co-operative study.
We undertook a prospective trial to evaluate terminal deoxynucleotidyl transferase activity as a predictor of responsiveness to… (More)
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