TCF7L2 wt Allele

Known as: TCF-4, TCF4, Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) wt Allele 
Human TCF7L2 wild-type allele is located in the vicinity of 10q25.3 and is approximately 217 kb in length. This allele, which encodes transcription… (More)
National Institutes of Health

Papers overview

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2013
2013
Haploinsufficiency of TCF4 causes Pitt-Hopkins syndrome (PTHS): a severe form of mental retardation with phenotypic similarities… (More)
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2011
2011
BACKGROUND Transcription factor 4 (TCF4 alias ITF2, E2-2, ME2 or SEF2) is a ubiquitous class A basic helix-loop-helix protein… (More)
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Highly Cited
2009
Highly Cited
2009
Colorectal cancer is one of the most common cancers worldwide. We tested the hypothesis that differences in the expression of… (More)
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Highly Cited
2007
Highly Cited
2007
Proneural factors represent <10 transcriptional regulators required for specifying all of the different neurons of the mammalian… (More)
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Highly Cited
2007
Highly Cited
2007
Ileal Crohn's disease (CD), a chronic mucosal inflammation, is characterized by two pertinent features: a specific decrease of… (More)
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2004
2004
Renal dysplasia, the major cause of childhood renal failure in humans, arises from perturbed renal morphogenesis and molecular… (More)
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2003
2003
Wnt signaling is essential during development while deregulation of this pathway frequently leads to the formation of various… (More)
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Highly Cited
2002
Highly Cited
2002
Genetic alterations of APC and CTNNB1 (β-catenin) have been identified in a number of human cancers including tumors arising in… (More)
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2002
2002
Lef/Tcf proteins belong to a family of architectural transcription factors that control developmental processes and play an… (More)
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1998
1998
The Tcf family of transcription factors, in association with beta-catenin, mediate Wnt signaling by transactivating downstream… (More)
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