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TCF7L2 wt Allele

Known as: TCF-4, TCF4, Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) wt Allele 
Human TCF7L2 wild-type allele is located in the vicinity of 10q25.3 and is approximately 217 kb in length. This allele, which encodes transcription… 
National Institutes of Health

Related topics

Related topics

12 relations
10q25.3Homo sapiensMelanogenesis PathwayNegative Regulation of Apoptosis

Broader (1)

TCF7L2 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Partial deletion of TCF4 in three generation family with non-syndromic intellectual disability, without features of Pitt-Hopkins syndrome.
2016
2016
β-Catenin and plakoglobin N- and C-tails determine ligand specificity.
beta-Catenin and plakoglobin are related proteins involved in the regulation of adherens junctions and desmosomes. Moreover, by… 
Review
2015
Review
2015
The second brain in autism spectrum disorder: could connexin 43 expressed in enteric glial cells play a role?
Autism spectrum disorder (ASD) is an umbrella term for a heterogeneous group of developmental disorders that present with… 
Review
2014
Review
2014
Association of Common Variants in TCF4 and PTPRG with Fuchs' Corneal Dystrophy: A Systematic Review and Meta-Analysis
Topic A meta-analysis of TCF4 and PTPRG gene variants in Fuchs' corneal dystrophy (FCD). Clinical relevance To identify novel… 
2014
2014
Regulation of TRAIL receptor expression by β-catenin in colorectal tumours.
Tumour-necrosis-factor-related apoptosis-inducing ligand (TRAIL) is being investigated as a targeted cancer therapeutic and the… 
2013
2013
Parent–child exome sequencing identifiesa de novo truncating mutation in TCF4 in non‐syndromic intellectual disability
To the Editor : Autosomal dominant mutations in the transcription factor TCF4 cause Pitt–Hopkins syndrome (PTHS; MIM#610954… 
2011
2011
Pitt–Hopkins syndrome should be in the differential diagnosis for males presenting with an ATR‐X phenotype
To the Editor : Pitt–Hopkins syndrome [PTHS (OMIM 6109 54)] is characterized by severe intellectual disability (ID), distinct… 
2009
2009
The Bcl-w promoter is activated by beta-catenin/TCF4 in human colorectal carcinoma cells.
2004
2004
β-Catenin and Plakoglobin N- and C-tails Determine Ligand Specificity*
β-Catenin and plakoglobin are related proteins involved in the regulation of adherens junctions and desmosomes. Moreover, by… 
Highly Cited
1999
Highly Cited
1999
A Possible Role for the High Mobility Group Box Transcription Factor Tcf-4 in Vertebrate Gut Epithelial Cell Differentiation*
The Wingless (Wg)/Wnt signaling pathway activates High Mobility Group (HMG)-box transcription factors of the T-cell Factor (Tcf… 
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