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10q25.3

A chromosome band present on 10q
National Institutes of Health

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10qChromosomesKCNK18 wt AlleleSHTN1 wt Allele

Papers overview

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Review
2016
Review
2016
Familial non-medullary thyroid cancer: unraveling the genetic maze.
Familial non-medullary thyroid cancer (FNMTC) constitutes 3-9% of all thyroid cancers. Out of all FNMTC cases, only 5% in the… 
2009
2009
Molecular (SNP) analyses of overlapping hemizygous deletions of 10q25.3 to 10qter in four patients: Evidence for HMX2 and HMX3 as candidate genes in hearing and vestibular function
We report on the analyses of four unrelated patients with de novo, overlapping, hemizygous deletions of the long arm of… 
2007
2007
Modifier locus for exencephaly in Cecr2 mutant mice is syntenic to the 10q25.3 region associated with neural tube defects in humans.
Neural tube defects (NTDs), the second most common birth defect in humans, are multifactorial with complex genetic and… 
2004
2004
Homozygous deletion and expression of PTEN and DMBT1 in human primary neuroblastoma and cell lines
Neuroblastoma is the most common pediatric solid tumor. Although many allelic imbalances have been described, a bona fide tumor… 
Highly Cited
2001
Highly Cited
2001
A 330 kb CENP‐A binding domain and altered replication timing at a human neocentromere
Centromere protein A (CENP‐A) is an essential centromere‐specific histone H3 homologue. Using combined chromatin… 
Highly Cited
2000
Highly Cited
2000
Assignment1 of the TCF-4 gene (TCF7L2) to human chromosome band 10q25.3
The TCF-4 gene (TCF7L2) is a member of the APC/ß-catenin/TCF pathway that is well known to play a crucial role in many… 
2000
2000
Cloning, chromosomal sublocalization of the human soluble aminopeptidase P gene (XPNPEP1) to 10q25.3 and conservation of the putative proton shuttle and metal ligand binding sites with XPNPEP2.
Human soluble ("cytosolic") aminopeptidase P (hsAmP) is an aminoacylprolyl hydrolase (EC 3.4.11.9) present in all tissues yet… 
Highly Cited
1999
Highly Cited
1999
Expression of DMBT1, a candidate tumor suppressor gene, is frequently lost in lung cancer.
DMBT1 is a candidate tumor suppressor gene located at 10q25.3-26.1. Homozygous deletion of the gene was found in a subset of… 
Highly Cited
1999
Highly Cited
1999
The genomic structure of the DMBT1 gene: evidence for a region with susceptibility to genomic instability
Increasing evidence has accumulated for an involvement of the inactivation of tumour suppressor genes at chromosome 10q in the… 
1992
1992
BEK, a receptor for multiple members of the fibroblast growth factor (FGF) family, maps to human chromosome 10q25.3----q26.
The gene for the fibroblast growth factor receptor BEK was assigned to human chromosome 10 by applying polymerase chain reaction… 
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