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TCF7L2 gene

Known as: TCF-4, transcription factor 7 like 2, T-CELL TRANSCRIPTION FACTOR 4, FORMERLY 
This gene plays a role in signal transduction and regulation of transcription.
National Institutes of Health

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Related topics

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Homo sapiensNegative Regulation of ApoptosisSignal TransductionTCF4 gene

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TCF7L2 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Age at onset of obesity, transcription factor 7-like 2 (TCF7L2) rs7903146 polymorphism, adiponectin levels and the risk of type 2 diabetes in obese patients
Introduction Interaction between obesity and genetic factors involved in the regulatory pathways of glucose homeostasis may play… 
2016
2016
Analysis of the interaction between transcription factor 7-like 2 genetic variants with nopal and wholegrain fibre intake: effects on anthropometric and metabolic characteristics in type 2 diabetes…
Abstract The transcription factor 7-like 2 (TCF7L2) genetic variants have shown differential effect on low-fat and high-fat diet… 
Review
2015
Review
2015
The Protective Effect of Transcription Factor 7-Like 2 Risk Allele rs7903146 against Elevated Fasting Plasma Triglyceride in Type 2 Diabetes: A Meta-Analysis
Background. The results from published studies regarding association of transcription factor 7-like 2 (TCF7L2) variant rs7903146… 
2014
2014
Association of the rs7903146 and rs12255372 polymorphisms in the TCF7L2 gene with type 2 diabetes in a population from northeastern Brazil.
Approximately 200 million people suffer from type 2 diabetes (T2D) worldwide, and the rapid increase in the prevalence of this… 
2011
2011
Association of TCF7L2 SNPs with age at onset of type 2 diabetes and proinsulin/insulin ratio but not with glucagon‐like peptide 1
Variants in TCF7L2 have been associated with the age at onset of type 2 diabetes in Mexican Americans. However, there is a lack… 
2011
2011
The expression of transcription factor 7-like 2 (TCF7L2) in fat and placental tissue from women with gestational diabetes.
2010
2010
Carriers of the TCF7L2 rs7903146 TT genotype have elevated levels of plasma glucose, serum proinsulin and plasma gastric inhibitory polypeptide (GIP) during a meal test
Aims/hypothesisThe transcription factor 7-like 2 (TCF7L2) rs7903146 T allele associates with type 2 diabetes in several… 
2008
2008
Loci of TCF7L2, HHEX and IDE on chromosome 10q and the susceptibility of their genetic polymorphisms to type 2 diabetes.
TCF7L2, HHEX and IDE on chromosome 10q23-25 reside within the linkage region for type 2 diabetes (T2D). Previous studies… 
2008
2008
Cold-inducible RNA binding protein (CIRP), a novel XTcf-3 specific target gene regulates neural development in Xenopus
BackgroundAs nuclear mediators of wnt/β-catenin signaling, Lef/Tcf transcription factors play important roles in development and… 
2001
2001
Genetic Alterations in the Human Tcf-4 Gene in Japanese Patients with Sporadic Gastrointestinal Cancers with Microsatellite Instability
Disruption of the APC/β-catenin/Tcf pathway has been proposed as an important step in the development of cancer. The Tcf-4… 
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