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TAP1 wt Allele

Known as: TAP1N, ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 2 Gene, RING4 
Human TAP1 wild-type allele is located in the vicinity of 6p21.3 and is approximately 9 kb in length. This allele, which encodes antigen peptide… 
National Institutes of Health

Related topics

Related topics

12 relations
6p21.3Antigen Presentation PathwayAntigen ProcessingBreast Carcinoma

Broader (1)

TAP1 gene

Papers overview

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Highly Cited
2006
Highly Cited
2006
ABCA3 as a Possible Cause of Drug Resistance in Childhood Acute Myeloid Leukemia
Background: A major issue in the treatment of acute myeloid leukemia (AML) is resistance to chemotherapeutic drugs. Multidrug… 
Highly Cited
2003
Highly Cited
2003
Characterization of human lymphocyte antigen class I antigen-processing machinery defects in renal cell carcinoma lesions with special emphasis on transporter-associated with antigen-processing down…
The HLA class I antigen-processing machinery (APM) plays a crucial role in the generation of peptides from endogenously… 
Highly Cited
1999
Highly Cited
1999
Susceptibility of Mice Deficient in CD1D or TAP1 to Infection with Mycobacterium tuberculosis
Cellular immunity against Mycobacterium tuberculosis controls infection in the majority of infected humans. Studies in mice have… 
Highly Cited
1999
Highly Cited
1999
Analysis of MHC encoded antigen-processing genes TAP1 and TAP2 polymorphisms in sarcoidosis.
Sarcoidosis is a chronic granulomatous disease of unknown etiology. Several studies have suggested involvement of human leukocyte… 
Highly Cited
1998
Highly Cited
1998
HLA class I antigen and transporter associated with antigen processing (TAP1 and TAP2) down-regulation in high-grade primary breast carcinoma lesions.
Five specimens of normal mammary tissue and 53 primary breast carcinoma lesions were tested for expression of HLA antigens and… 
Highly Cited
1996
Highly Cited
1996
A functionally defective allele of TAP1 results in loss of MHC class I antigen presentation in a human lung cancer
Tumours express a variety of novel epitopes which represent potential immune targets, and thus clinically evident tumours are… 
Highly Cited
1995
Highly Cited
1995
Discordant patterns of linkage disequilibrium of the peptide-transporter loci within the HLA class II region.
Disequilibrium between genetic markers is expected to decline monotonically with recombinational map distance. We present… 
Highly Cited
1994
Highly Cited
1994
Polymorphism of antigen processing (TAP, LMP) and HLA class II genes in celiac disease.
Highly Cited
1993
Highly Cited
1993
Alleles and haplotypes of the MHC-encoded ABC transporters TAP1 and TAP2
TAP1 and TAP2 are two major histocompatibility complex (MHC) genes, located between HLA-DP and -DQ, whose products form a… 
Highly Cited
1992
Highly Cited
1992
Ham-2 corrects the class I antigen-processing defect in RMA-S cells
THE murine major histocompatibility complex (MHC) contains two genes (Ham-1 and Ham-2) that encode members of a super-family of… 
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