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TAN 67

Known as: TAN-67 
 
National Institutes of Health

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2 relations

Broader (2)

AnalgesicsQuinolines

Papers overview

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2005
2005
The non-peptidic delta opioid receptor agonist TAN-67 enhances dopamine efflux in the nucleus accumbens of freely moving rats via a mechanism that involves both glutamate and free radicals
The activation of the delta-opioid receptors in the nucleus accumbens is known to induce a large and rapid increase of accumbal… Expand
Highly Cited
2001
Highly Cited
2001
Differential activation of extracellular signal regulated kinase isoforms in preconditioning and opioid-induced cardioprotection.
Stimulation of the delta(1)-opioid receptor has been shown to trigger ischemic preconditioning (IPC). Additionally, myocardial… Expand
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Highly Cited
2001
Highly Cited
2001
Essential activation of PKC-δ in opioid-initiated cardioprotection
oid receptor stimulation with TAN-67 or D-Ala 2 -D-Leu 5 -enkephalin (DADLE) in a rat model of myocardial infarction induced by a… Expand
Highly Cited
2000
Highly Cited
2000
Opioid-induced cardioprotection against myocardial infarction and arrhythmias: mitochondrial versus sarcolemmal ATP-sensitive potassium channels.
We examined the role of the sarcolemmal and mitochondrial ATP-sensitive potassium (K(ATP)) channel in a rat model of myocardial… Expand
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Highly Cited
1999
Highly Cited
1999
Opioid-induced second window of cardioprotection: potential role of mitochondrial KATP channels.
Opioids have been previously shown to confer short-term cardioprotection against a prolonged ischemic insult. Therefore, the… Expand
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Highly Cited
1998
Highly Cited
1998
TAN-67, a δ1-opioid receptor agonist, reduces infarct size via activation of Gi/o proteins and KATP channels.
We have previously shown that delta (δ)-opioid receptors, most notably δ1, are involved in the cardioprotective effect of… Expand
Highly Cited
1998
Highly Cited
1998
TAN-67, a delta 1-opioid receptor agonist, reduces infarct size via activation of Gi/o proteins and KATP channels.
We have previously shown that delta (delta)-opioid receptors, most notably delta 1, are involved in the cardioprotective effect… Expand
Highly Cited
1998
Highly Cited
1998
Rational drug design and synthesis of a highly selective nonpeptide delta-opioid agonist, (4aS*,12aR*)-4a-(3-hydroxyphenyl)-2-methyl- 1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridine (TAN-67).
We designed highly selective non-peptide agonists for the delta-opioid receptor. On the basis of the "message-address" concept in… Expand
1997
1997
Delta-1 opioid receptor-mediated antinociceptive properties of a nonpeptidic delta opioid receptor agonist, (-)TAN-67, in the mouse spinal cord.
The effects of enantiomorphs of TAN-67 (2-methyl-4a alpha-(3-hydroxyphenyl)-1,2,3,4,4a,5,12,12a alpha-octahydro-quinolino[2,3,3-g… Expand
Highly Cited
1995
Highly Cited
1995
Antinociceptive effects of the selective non-peptidic delta-opioid receptor agonist TAN-67 in diabetic mice.
The antinociceptive potencies of 2-methyl-4 alpha alpha-(3-hydroxyphenyl)-1,2,3,4,4a,5,12,12 alpha alpha-octahydro-quinolino[2,3… Expand
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