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TAN 67

Known as: TAN-67 
National Institutes of Health

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2 relations

Broader (2)

AnalgesicsQuinolines

Papers overview

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Highly Cited
2011
Highly Cited
2011
The novel δ opioid receptor agonist KNT-127 produces antidepressant-like and antinociceptive effects in mice without producing convulsions
Highly Cited
2010
Highly Cited
2010
Design and synthesis of KNT-127, a δ-opioid receptor agonist effective by systemic administration.
2009
2009
Design and synthesis of novel delta opioid receptor agonists and their pharmacologies.
Highly Cited
2001
Highly Cited
2001
Differential activation of extracellular signal regulated kinase isoforms in preconditioning and opioid-induced cardioprotection.
Stimulation of the delta(1)-opioid receptor has been shown to trigger ischemic preconditioning (IPC). Additionally, myocardial… 
Highly Cited
2001
Highly Cited
2001
Essential activation of PKC-δ in opioid-initiated cardioprotection
oid receptor stimulation with TAN-67 or D-Ala 2 -D-Leu 5 -enkephalin (DADLE) in a rat model of myocardial infarction induced by a… 
Highly Cited
2001
Highly Cited
2001
ERK and p38 MAP kinase activation are components of opioid-induced delayed cardioprotection
Abstract Opioids have been previously shown to confer acute and delayed cardioprotection against a prolonged ischemic insult. We… 
1999
1999
Involvement of dopamine D1 and D2 receptors in the ethanol-associated place preference in rats exposed to conditioned fear stress
Highly Cited
1998
Highly Cited
1998
TAN-67, a δ1-opioid receptor agonist, reduces infarct size via activation of Gi/o proteins and KATP channels.
We have previously shown that delta (δ)-opioid receptors, most notably δ1, are involved in the cardioprotective effect of… 
Highly Cited
1998
Highly Cited
1998
TAN-67, a delta 1-opioid receptor agonist, reduces infarct size via activation of Gi/o proteins and KATP channels.
We have previously shown that delta (delta)-opioid receptors, most notably delta 1, are involved in the cardioprotective effect… 
Highly Cited
1998
Highly Cited
1998
Rational drug design and synthesis of a highly selective nonpeptide delta-opioid agonist, (4aS*,12aR*)-4a-(3-hydroxyphenyl)-2-methyl- 1,2,3,4,4a,5,12,12a-octahydropyrido[3,4-b]acridine (TAN-67).
We designed highly selective non-peptide agonists for the delta-opioid receptor. On the basis of the "message-address" concept in… 
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