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TACR1 wt Allele

Known as: Tachykinin Receptor 1 wt Allele, TAC1R, Tachykinin Receptor 1 (Substance P Receptor; Neurokinin-1 Receptor) Gene 
Human TACR1wild-type allele is located in the vicinity of 2p13.1 and is approximately 150 kb in length. This allele, which encodes substance-P… 
National Institutes of Health

Related topics

Related topics

8 relations
2p12G Protein-Coupled Receptor SignalingLigand BindingReceptor Signaling

Broader (1)

TACR1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Brain neurokinin-1 receptor availability in never-medicated patients with major depression - A pilot study.
2016
2016
The NK 1 R-/-mouse phenotype suggests that small body size , with a sex-and diet-dependent excess in body mass and fat , are physical biomarkers for a human endophenotype with vulnerability to…
The abnormal behaviour of NK1R-/mice (locomotor hyperactivity, inattentiveness and impulsivity in the 5-Choice Serial Reaction… 
Highly Cited
2014
Highly Cited
2014
Antitumor activity of neurokinin-1 receptor antagonists in MG-63 human osteosarcoma xenografts.
Osteosarcoma is a highly malignant bone tumor in children and adolescents. Aprepitant is a selective high‑affinity antagonist of… 
2014
2014
Modeling and simulation approach to support dosing and study design requirements for treating HIV-related neuropsychiatric disease with the NK1-R antagonist aprepitant.
Psychiatric illness is common in HIV-infected patients and underlines the importance for screening not only for cognitive… 
2009
2009
Acute inflammation induces segmental, bilateral, supraspinally mediated opioid release in the rat spinal cord, as measured by μ-opioid receptor internalization
Highly Cited
2000
Highly Cited
2000
NK1, NK2 and NK3 tachykinin receptor localization and tachykinin distribution in the ileum of the mouse
Tachykinin receptors NK1r, NK2r and NK3r bind tachykinins with different affinities and share pharmacological and molecular… 
1992
1992
Assignment of the rat genes coding for substance P receptor, substance K receptor, and neuromedin K receptor to chromosomes 4, 20, and 2, respectively.
Three tachykinin receptor genes: substance P receptor gene (gene symbol; TAC1R), substance K receptor gene (TAC2R), and… 
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