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Suppressor of Cytokine Signaling 3

Known as: SOCS-3, CIS-3, STAT-Induced STAT Inhibitor 3 
Suppressor of cytokine signaling 3 (225 aa, ~25 kDa) is encoded by the human SOCS3 gene. This protein is involved in the down-regulation of cytokine… 
National Institutes of Health

Related topics

Related topics

17 relations
Adipocytokine Signaling PathwayCytokine SignalingCytoplasmic matrixErythropoietin Signaling Pathway

Papers overview

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2015
2015
Managing Diabetes and Liver Disease Association Guidelines (Consensus) Development
2009
2009
IL-1β-induced chemokine and Fas expression are inhibited by suppressor of cytokine signalling-3 in insulin-producing cells
Aims/hypothesisChemokines recruit activated immune cells to sites of inflammation and are important mediators of insulitis… 
2008
2008
SOCS-3 Inhibits E2F/DP-1 Transcriptional Activity and Cell Cycle Progression via Interaction with DP-1
Recent studies using SOCS family knock-out mice have suggested that SOCS proteins have multiple biological functions in addition… 
2006
2006
Bis(1 degree-amino)cyclodistib(III)azanes: the first structural characterization of cis and trans isomers of a single cyclodipnict(III)azane.
The dichlorocyclodistib(III)azane [ClSb(mu-NtBu)]2 (1) has been shown to exist as the cis isomer in the solid state. A series of… 
2004
2004
Activity of the suppressor of cytokine signaling-3 promoter in human non-small-cell lung cancer.
The Janus kinase (JAKs)/signal transducers and activators of transcription (STAT) signaling pathway is controlled by a classical… 
2003
2003
Growth Hormone Down-Regulation of Interleukin-1&bgr; and Interleukin-6 Induced Acute Phase Protein Gene Expression is Associated with Increased Gene Expression of Suppressor of Cytokine Signal-3
Severe burn induces the hepatic acute phase response. We previously showed that recombinant human growth hormone (GH) treatment… 
2002
2002
Interleukin-10 and cAMP-elevating agents cooperate to induce suppressor of cytokine signaling-3 via a protein kinase A-independent signal.
We have recently shown that IL-10 represents an efficient stimulus for suppressor of cytokine signalling (SOCS)-3 mRNA expression… 
2002
2002
Isoproterenol is a positive regulator of the suppressor of cytokine signaling-3 gene expression in 3T3-L1 adipocytes.
SOCS (suppressor of cytokine signaling)-3 has recently been shown to be an insulin- and tumor necrosis factor (TNF)-alpha-induced… 
1978
1978
Stereoselective effects of cis- and trans-cyclopropylbis (dioxopiperazines) related to ICRF-159 on metastases of hamster lung adenocarcinoma.
The synthesis for cis-4,4' (1,2-cyclopropanediyl)bis(2,6-piperazinedione) (cis-3) is discussed. Stereoselective effects on… 
Review
1970
Review
1970
Needs--of People and Their Communities--and the Adult Educator: A Review of the Literature of Need Determination.
DOCUMENT RESUME Al 000 536 McMahon, Ernest E. Needs--of People and Their Communities--and the Adult Educator: A Review of the… 
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