Sulfonylurea Compounds

BACKGROUND Latent autoimmune diabetes in adults (LADA) is a slowly developing type 1 diabetes. OBJECTIVES To compare… Expand

Insulin resistance in muscle and liver and β-cell failure represent the core pathophysiologic defects in type 2 diabetes. It now… Expand

BACKGROUND Unlike most antihyperglycaemic drugs, glucagon-like peptide-1 (GLP-1) receptor agonists have a glucose-dependent… Expand

BACKGROUND During the United Kingdom Prospective Diabetes Study (UKPDS), patients with type 2 diabetes mellitus who received… Expand

OBJECTIVE This study evaluated the ability of the incretin mimetic exenatide (exendin-4) to improve glycemic control in patients… Expand

CONTEXT Treatment with diet alone, insulin, sulfonylurea, or metformin is known to improve glycemia in patients with type 2… Expand

Background Improved blood-glucose control decreases the progression of diabetic microvascular disease, but the effect on… Expand

BACKGROUND Improved blood-glucose control decreases the progression of diabetic microvascular disease, but the effect on… Expand

BACKGROUND In patients with type 2 diabetes, intensive blood-glucose control with insulin or sulphonylurea therapy decreases… Expand

A member of the inwardly rectifying potassium channel family was cloned here. The channel, called BIR (Kir6.2), was expressed in… Expand