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Glyburide

Known as: Glyburide [Chemical/Ingredient], Glibenclamida, Glibenclamide 
A sulfonamide urea derivative with antihyperglycemic activity that can potentially be used to decrease cerebral edema. Upon administration, glyburide… 
National Institutes of Health

Related topics

Related topics

36 relations

Narrower (14)

5-iodo-2-hydroxyglyburide71-5WBM 208Daonil
CYP2C9 protein, humanCarbutamideDiabetesDiabetes Mellitus

Broader (2)

Hypoglycemic AgentsSulfonylurea Compounds

Papers overview

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Highly Cited
1996
Highly Cited
1996
Morphine mimics the cardioprotective effect of ischemic preconditioning via a glibenclamide-sensitive mechanism in the rat heart.
Previous results from our laboratory have suggested that opioid receptors are involved in ischemic preconditioning (PC) in rat… 
Highly Cited
1994
Highly Cited
1994
Ischemic Preconditioning During Coronary Angioplast Is Prevented by Glibenclamide, a Selective ATP‐Sensitive K+ Channel Blocker
BackgroundBrief episodes of ischemia render the heart more resistant to subsequent ischemia; this phenomenon has been called… 
Highly Cited
1992
Highly Cited
1992
Blockade of ATP-sensitive potassium channels prevents myocardial preconditioning in dogs.
Single or multiple brief periods of ischemia (preconditioning) have been shown to protect the myocardium from infarction after a… 
Highly Cited
1992
Highly Cited
1992
Ischemic preconditioning protects against infarction in rat heart.
We examined the anti-infarct effect of ischemic preconditioning in the rat heart. All hearts were subjected to 30 min of regional… 
Highly Cited
1992
Highly Cited
1992
Evidence that nitric oxide does not mediate the hyperpolarization and relaxation to acetylcholine in the rat small mesenteric artery
1 Acetylcholine caused a concentration‐dependent smooth muscle hyperpolarization and relaxation in rat small mesenteric arteries… 
Highly Cited
1992
Highly Cited
1992
Effect of ATP-sensitive K+ channel regulators on cystic fibrosis transmembrane conductance regulator chloride currents
The cystic fibrosis transmembrane conductance regulator (CFTR) is a Cl- channel that is regulated by cAMP-dependent… 
Highly Cited
1991
Highly Cited
1991
ATP-regulated K+ channels protect the myocardium against ischemia/reperfusion damage.
Highly Cited
1990
Highly Cited
1990
Cyclosporin A drug interactions. Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes.
In previous papers we demonstrated that cyclosporin A (CsA) was specifically oxidized in rabbit and human liver by cytochrome P… 
Highly Cited
1989
Highly Cited
1989
Hyperpolarizing vasodilators activate ATP-sensitive K+ channels in arterial smooth muscle.
Vasodilators are used clinically for the treatment of hypertension and heart failure. The effects of some vasodilators seem to be… 
Highly Cited
1985
Highly Cited
1985
THE SULPHONYLUREA RECEPTOR MAY BE AN ATP-SENSITIVE POTASSIUM CHANNEL
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