Glyburide

Known as: Glyburide [Chemical/Ingredient], Glibenclamida, Glibenclamide 
A sulfonamide urea derivative with antihyperglycemic activity that can potentially be used to decrease cerebral edema. Upon administration, glyburide… (More)
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
OBJECTIVE ADOPT (A Diabetes Outcome Progression Trial) demonstrated that initial monotherapy with rosiglitazone provided superior… (More)
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Highly Cited
2010
Highly Cited
2010
CONTEXT An increase in bone fractures has been observed in women taking thiazolidinediones. OBJECTIVE The objective of the… (More)
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Highly Cited
2009
Highly Cited
2009
Glyburide's pharmacokinetics (PK) and pharmacodynamics have not been studied in women with gestational diabetes mellitus (GDM… (More)
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Highly Cited
2007
Highly Cited
2007
Sulfonylureas (SU) with glucagon-like peptide-1 (GLP-1)-based therapy are an emerging therapeutic combination for type 2 diabetes… (More)
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Highly Cited
2006
Highly Cited
2006
BACKGROUND The efficacy of thiazolidinediones, as compared with other oral glucose-lowering medications, in maintaining long-term… (More)
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Highly Cited
2000
Highly Cited
2000
BACKGROUND Women with gestational diabetes mellitus are rarely treated with a sulfonylurea drug, because of concern about… (More)
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Highly Cited
1998
Highly Cited
1998
The mitochondrial KATP channel (mitoKATP) is hypothesized to be the receptor for the cardioprotective effects of K+ channel… (More)
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Highly Cited
1995
Highly Cited
1995
BACKGROUND Sulfonylurea drugs have been the only oral therapy available for patients with non-insulin-dependent diabetes mellitus… (More)
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Highly Cited
1991
Highly Cited
1991
No data exist concerning human placental transfer of oral hypoglycemic agents during pregnancy. This study characterizes the… (More)
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