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Carbutamide

Known as: Benzenesulfonamide, 4-amino-N-((butylamino)carbonyl)-, Sulfaninylbutylurea, Glybutamide 
A first-generation sulfonylurea with hypoglycemic activity. Carbutamide was one of the first sulfonylurea compounds used but was withdrawn from the… Expand
National Institutes of Health

Papers overview

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Highly Cited
2002
Highly Cited
2002
Clinical features similar to diabetes mellitus were described 3000 years ago by the ancient Egyptians. The term "diabetes" was… Expand
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Highly Cited
2000
Highly Cited
2000
Aims This study was designed to test the efficacy and safety of low‐dose rosiglitazone, a potent, insulin‐sensitizing… Expand
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1965
1965
On the basis of a six-year investigation in which 9,214 diabetics were treated with oral agents, we were able to confirm the… Expand
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Highly Cited
1960
Highly Cited
1960
The hereditary obese-hyperglycemic syndrome is a Mendelian recessive condition which has been intensively studied in the last few… Expand
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Highly Cited
1959
Highly Cited
1959
Oral treatment with carbutamide (BZ-55) for 7 weeks (2.5 gm/kg of ground chow) left the food intake and rate of weight gain of… Expand
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Highly Cited
1959
Highly Cited
1959
The acute administration of carbutamide was found to have a hypoglycemic effect in fasted normal mice, while it had no definite… Expand
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1958
1958
Summary and conclusions Insulin was injected in different doses and at different rates into either the femoral or the portal vein… Expand
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1957
1957
  • M. Root
  • Diabetes
  • 1957
  • Corpus ID: 22735203
 
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1957
1957
From December 1955, through August 1956, we used sulfonylurea compounds in 620 patients with diabetes. Of this number 380… Expand
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1956
1956
Summary and Conclusions The mechanism of the hypoglycemic action of carbutamide in normal dogs was studied by means of pancreatic… Expand
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