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Src Homology 2 Domain-Containing, Transforming Protein 1

Known as: SHC1 Protein, SHC-Transforming Protein 1, Src Homology 2 Domain Containing Transforming Protein C1 
An SHC-signaling adaptor protein that transduces PHOSPHOTYROSINE-dependent signals downstream of RECEPTOR PROTEIN-TYROSINE KINASES and non-receptor… Expand
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
The nucleus is mechanically coupled to the three cytoskeletal elements in the cell via linkages maintained by the LINC complex… Expand
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2013
2013
3D structure of CysLT2 receptor was constructed by using homology modeling and molecular simulations. The binding pocket of… Expand
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2011
2011
We present a comparative account on 3D-structures of human type-1 receptor (AT1) for angiotensin II (AngII), modeled using three… Expand
Highly Cited
2009
Highly Cited
2009
Homology modeling of the human A(2A) adenosine receptor (AR) based on bovine rhodopsin predicted a protein structure that was… Expand
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2009
2009
When X-ray structure of a ligand-bound receptor is not available, homology models of the protein of interest can be used to… Expand
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Highly Cited
2005
Highly Cited
2005
In this paper, we describe homology modeling of the alpha1A receptor based on the X-ray structure of bovine rhodopsin. The… Expand
Highly Cited
2005
Highly Cited
2005
Inflammation contributes to insulin resistance in diabetes and obesity. Mouse Pelle-like kinase (mPLK, homolog of human IL-1… Expand
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Highly Cited
2004
Highly Cited
2004
Angiopoietin-1 can promote migration, sprouting, and survival of endothelial cells through activation of different signaling… Expand
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Highly Cited
2003
Highly Cited
2003
The production of red blood cells is tightly regulated by erythropoietin (Epo). The phosphoinositide 3-kinase (PI 3-kinase… Expand
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Highly Cited
2002
Highly Cited
2002
Recent studies have shown that phox homology (PX) domains act as phosphoinositide-binding motifs. The majority of PX domains… Expand
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