SHC1 gene

Known as: p46, SHC (Src Homology 2 Domain Containing) Transforming Protein 1 Gene, SHC1 
This gene is involved in signal transduction and plays a role in aging.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1984-2018
05101519842018

Papers overview

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Highly Cited
2011
Highly Cited
2011
We generated a transgenic mouse line that expresses the Cre recombinase under the control of the Ncr1 (p46) promoter. Cre… (More)
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2009
2009
The 2',5'-oligoadenylate synthetase (OAS) and its downstream effector RNase L play important roles in host defense against virus… (More)
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2008
2008
Cooperation between the Neu/ErbB-2 and transforming growth factor beta (TGF-beta) signaling pathways enhances the invasive and… (More)
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Highly Cited
2008
Highly Cited
2008
To explore the in vivo significance of ShcA during mammary tumorigenesis, we used mice expressing several phosphotyrosine… (More)
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Highly Cited
2007
Highly Cited
2007
Erk1/Erk2 MAP kinases are key regulators of cell behaviour and their activation is generally associated with tyrosine kinase… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Autoimmune retinal degeneration may occur in patients who present with sudden or, less commonly, subacute loss of… (More)
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Highly Cited
2000
Highly Cited
2000
The ShcA gene products have served as a model for the analysis of phosphotyrosine-recognition domains, and for the functions of… (More)
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1999
1999
A conscious rabbit model was used to study the effect of ischemic preconditioning (PC) on stress-activated kinases [c-Jun NH(2… (More)
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Highly Cited
1998
Highly Cited
1998
After culture in interleukin (IL)-2, natural killer (NK) cells acquire an increased capability of mediating non-major… (More)
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Highly Cited
1997
Highly Cited
1997
Limited information is available on the surface molecules that are involved in natural killer (NK) cell triggering. In this study… (More)
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