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SHC1 gene

Known as: p46, SHC (Src Homology 2 Domain Containing) Transforming Protein 1 Gene, SHCA 
This gene is involved in signal transduction and plays a role in aging.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Cell-surface receptors frequently use scaffold proteins to recruit cytoplasmic targets, but the rationale for this is uncertain… Expand
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Highly Cited
2011
Highly Cited
2011
We generated a transgenic mouse line that expresses the Cre recombinase under the control of the Ncr1 (p46) promoter. Cre… Expand
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Highly Cited
2008
Highly Cited
2008
Summary RbAp46 and RbAp48 (pRB-associated proteins p46 and p48, also known as RBBP7 and RBBP4, respectively) are highly… Expand
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Highly Cited
2002
Highly Cited
2002
Ephrin-B/EphB family proteins are implicated in bidirectional signaling and were initially defined through the function of their… Expand
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Review
2001
Review
2001
The adapter protein Shc was initially identified as an SH2 containing proto-oncogene involved in growth factor signaling. Since… Expand
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Highly Cited
1999
Highly Cited
1999
A conscious rabbit model was used to study the effect of ischemic preconditioning (PC) on stress-activated kinases [c-Jun NH2… Expand
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Highly Cited
1998
Highly Cited
1998
After culture in interleukin (IL)-2, natural killer (NK) cells acquire an increased capability of mediating non–major… Expand
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Highly Cited
1998
Highly Cited
1998
BACKGROUND In eukaryotic cells, newly synthesized histone H4 is acetylated at lysines 5 and 12, a transient modification erased… Expand
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Highly Cited
1997
Highly Cited
1997
Limited information is available on the surface molecules that are involved in natural killer (NK) cell triggering. In this study… Expand
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Highly Cited
1995
Highly Cited
1995
The major regulators of the c-jun promoter are ATF-2 and c-Jun. They act as pre-bound heterodimers on two 'AP-1-like' sites, and… Expand
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