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SHC1 gene

Known as: p46, SHC (Src Homology 2 Domain Containing) Transforming Protein 1 Gene, SHCA 
This gene is involved in signal transduction and plays a role in aging.
National Institutes of Health

Related topics

Related topics

7 relations
Cell Proliferation Regulatory ProcessNFKB2 geneSHC1 protein, humanSignal Transduction

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SHC1 wt Allele

Papers overview

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Highly Cited
2007
Highly Cited
2007
Study of antimutagenic and antioxidant activities of gallic acid and 1,2,3,4,6-pentagalloylglucose from Pistacia lentiscus. Confirmation by microarray expression profiling.
Highly Cited
2005
Highly Cited
2005
Variation in antiviral 2',5'-oligoadenylate synthetase (2'5'AS) enzyme activity is controlled by a single-nucleotide polymorphism at a splice-acceptor site in the OAS1 gene.
It is likely that human genetic differences mediate susceptibility to viral infection and virus-triggered disorders. OAS genes… 
Highly Cited
2005
Highly Cited
2005
Yersiniophage phiR1-37 is a tailed bacteriophage having a 270 kb DNA genome with thymidine replaced by deoxyuridine.
Bacteriophage piR1-37 was isolated based on its ability to infect strain YeO3-R1, a virulence-plasmid-cured O antigen-negative… 
Highly Cited
2003
Highly Cited
2003
Skeletal Muscle Signaling Pathway through the Dystrophin Glycoprotein Complex and Rac1*
The dystrophin glycoprotein complex has been proposed to be involved in signal transduction. Here we have shown that laminin… 
Highly Cited
2002
Highly Cited
2002
Isoform-specific knockdown and expression of adaptor protein ShcA using small interfering RNA.
Many eukaryotic genes are expressed as multiple isoforms through the differential utilization of transcription/translation… 
Highly Cited
2000
Highly Cited
2000
Diagnosis and Differentiation of Mycoplasma hyopneumoniae and Mycoplasma hyorhinis Infections in Pigs by PCR Amplification of the p36 and p46 Genes
ABSTRACT The genome of Mycoplasma hyopneumoniae encodes several immunodominant proteins, including a cytosolic protein (p36… 
Highly Cited
1999
Highly Cited
1999
Evaluation of the role of mitogen-activated protein kinases in the expression of inducible nitric oxide synthase by IFN-gamma and TNF-alpha in mouse macrophages.
The expression of inducible nitric oxide synthase (iNOS) by macrophages is stimulated by coexposure to IFN-gamma and a number of… 
Highly Cited
1999
Highly Cited
1999
PKC-dependent activation of p46/p54 JNKs during ischemic preconditioning in conscious rabbits.
A conscious rabbit model was used to study the effect of ischemic preconditioning (PC) on stress-activated kinases [c-Jun NH2… 
Highly Cited
1998
Highly Cited
1998
Human BAG-1/RAP46 protein is generated as four isoforms by alternative translation initiation and overexpressed in cancer cells
Previously, a Bcl-2-interacting protein, BAG-1, was cloned from mouse cells and was shown to interact with several other proteins… 
Highly Cited
1993
Highly Cited
1993
The p46 subunit of eukaryotic initiation factor (eIF)-4F exchanges with eIF-4A.
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