Skip to search formSkip to main contentSkip to account menu

SHC1 wt Allele

Known as: SHC, SHC (Src Homology 2 Domain Containing) Transforming Protein 1 wt Allele, SHCA 
Human SHC1 wild-type allele is located in the vicinity of 1q21 and is approximately 12 kb in length. This allele, which encodes SHC-transforming… 
National Institutes of Health

Related topics

Related topics

31 relations
1q21Angiogenesis PathwayAngiotensin II Signaling PathwayB Cell Receptor Signaling Pathway

Broader (1)

SHC1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Protein-tyrosine phosphatase epsilon regulates Shc signaling in a kinase-specific manner: increasing coherence in tyrosine phosphatase signaling.
Individual protein tyrosine kinases and phosphatases target multiple substrates; this may generate conflicting signals, possibly… 
2004
2004
Non-redundant Role of Shc in Erk Activation by Cytoskeletal Reorganization*
We have shown previously that cytoskeletal reorganization (CSR) induced by pharmacological reagents such as colchicine or… 
2003
2003
Tip link loss and recovery on chick short hair cells following intense exposure to sound
2002
2002
Discrimination between phosphotyrosine-mediated signaling properties of conventional and neuronal Shc adapter molecules
The phosphotyrosine (pTyr) adapter Shc/ShcA is a major connector in various tyrosine kinase signalings following a variety of… 
2002
2002
Membrane localization of Src homology 2-containing inositol 5'-phosphatase 2 via Shc association is required for the negative regulation of insulin signaling in Rat1 fibroblasts overexpressing…
Lipid phosphatase SHIP2 [Src homology 2 (SH2)-containing inositol 5'-phosphatase 2] has been shown to be a physiologically… 
1999
1999
Insulin-induced tyrosine phosphorylation of Shc in liver, muscle and adipose tissue of insulin resistant rats
Highly Cited
1997
Highly Cited
1997
Signaling Functions of the Tyrosine Residues in the βc Chain of the Granulocyte-Macrophage Colony-Stimulating Factor Receptor
The granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor (GMR) is a heterodimeric receptor expressed by myeloid… 
Highly Cited
1996
Highly Cited
1996
Activation-induced Association of a 145-kDa Tyrosine-phosphorylated Protein with Shc and Syk in B Lymphocytes and Macrophages (*)
Engagement of many cell surface receptors results in tyrosine phosphorylation of an overlapping set of protein substrates. Some… 
1996
1996
Nerve growth factor induces a multimeric TrkA receptor complex in neuronal cells that includes Crk, SHC and PLC-gamma 1 but excludes P130CAS.
Binding of nerve growth factor (NGF) to the TrkA receptor results in homodimerization, and activation of the intrinsic tyrosine… 
1986
1986
Motor activity changes and conditioned taste aversions induced by administration of scopolamine in rats: Role of the area postrema
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)