SHC1 wt Allele

Known as: SHC, SHC (Src Homology 2 Domain Containing) Transforming Protein 1 wt Allele, SHCA 
Human SHC1 wild-type allele is located in the vicinity of 1q21 and is approximately 12 kb in length. This allele, which encodes SHC-transforming… (More)
National Institutes of Health

Papers overview

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2008
2008
Cooperation between the Neu/ErbB-2 and transforming growth factor beta (TGF-beta) signaling pathways enhances the invasive and… (More)
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2004
2004
The etiology and progression of a variety of human malignancies are linked to the deregulation of receptor tyrosine kinases (RTKs… (More)
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2002
2002
The phosphotyrosine (pTyr) adapter Shc/ShcA is a major connector in various tyrosine kinase signalings following a variety of… (More)
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2001
2001
Previously we found that the availability of ShcA adapter is maximal in neural stem cells but that it is absent in mature neurons… (More)
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Highly Cited
2000
Highly Cited
2000
Nerve growth factor binds to the TrkA and p75(NTR) (p75) and generates signals leading to neuronal cell survival, differentiation… (More)
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1999
1999
The FLT3 receptor tyrosine kinase and its ligand, FL, regulate the development of hematopoietic stem cells and early B lymphoid… (More)
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Highly Cited
1998
Highly Cited
1998
Prostate cancer (PCA) is the most common nonskin malignancy and the second leading cause of cancer deaths in United States males… (More)
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Review
1998
Review
1998
In mammalian systems, SH2-containing cytoplasmic signalling molecules are known to play an important role in determining cell… (More)
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1997
1997
The adult mammalian brain comprises many functionally distinct neuronal types, which are generated during development as a result… (More)
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1996
1996
Engagement of many cell surface receptors results in tyrosine phosphorylation of an overlapping set of protein substrates. Some… (More)
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