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- Publications
- Influence
Neurobiological effects of intraventricular propionic acid in rats: Possible role of short chain fatty acids on the pathogenesis and characteristics of autism spectrum disorders
- D. MacFabe, D. Cain, Karina Rodríguez-Capote, Andrew E. Franklin, K. Ossenkopp
- Biology, Medicine
- Behavioural Brain Research
- 10 January 2007
Clinical observations suggest that certain gut and dietary factors may transiently worsen symptoms in autism spectrum disorders (ASD), epilepsy and some inheritable metabolic disorders. Propionic… Expand
Sexually dimorphic spatial learning in meadow voles Microtus pennsylvanicus and deer mice Peromyscus maniculatus.
- L. A. Galea, M. Kavaliers, K. Ossenkopp
- Biology, Medicine
- The Journal of experimental biology
- 1996
A number of studies examining developmental, neural and hormonal aspects of sexually dimorphic spatial learning (Morris water-maze) in meadow voles (Microtus pennsylvanicus) and deer mice (Peromyscus… Expand
Intracerebroventricular injection of propionic acid, an enteric bacterial metabolic end-product, impairs social behavior in the rat: Implications for an animal model of autism
- S. Shultz, D. MacFabe, K. Ossenkopp, S. Scratch, D. Cain
- Psychology, Medicine
- Neuropharmacology
- 1 May 2008
Environmental, dietary, and gastrointestinal factors may contribute to autism spectrum disorders (ASD). Propionic acid (PPA) is a short chain fatty acid, a metabolic end-product of enteric bacteria… Expand
Sex differences in performance in the Morris water maze and the effects of initial nonstationary hidden platform training.
- T. Perrot-Sinal, M. A. Kostenuik, K. Ossenkopp, M. Kavaliers
- Psychology, Medicine
- Behavioral neuroscience
- 1 December 1996
Sex differences in rats' performance on a stationary hidden-platform task (spatial task) in the Morris water maze and the effects of initial nonstationary hidden platform training (NSP training) were… Expand
Effects of the enteric bacterial metabolic product propionic acid on object-directed behavior, social behavior, cognition, and neuroinflammation in adolescent rats: Relevance to autism spectrum…
- D. MacFabe, Nathan E. Cain, F. Boon, K. Ossenkopp, D. Cain
- Psychology, Medicine
- Behavioural Brain Research
- 2 February 2011
Recent evidence suggests that a variety of environmental factors, including dietary and gastrointestinal agents, may contribute to autism spectrum disorders (ASD). Here we administered propionic acid… Expand
Toxin-induced conditioned changes in taste reactivity and the role of the chemosensitive area postrema
- K. Ossenkopp, L. Eckel
- Biology, Medicine
- Neuroscience & Biobehavioral Reviews
- 1 March 1995
Conditioned taste avoidances (CTAs) are an important component of behavioral regulation of ingestion. In the laboratory CTAs can be produced by pairing a novel taste stimulus with the physiological… Expand
A Novel Rodent Model of Autism: Intraventricular Infusions of Propionic Acid Increase Locomotor Activity and Induce Neuroinflammation and Oxidative Stress in Discrete Regions of Adult Rat Brain
- D. MacFabe, Karina Rodríguez-Capote, +8 authors K. Ossenkopp
- Chemistry
- 30 June 2008
Innate neuroinflammatory changes, increased oxidative stress and disorders of glutathione metabolism may be involved in the pathophysiology of autism spectrum disorders (ASD). Propionic acid (PPA) is… Expand
Pain perception and electromagnetic fields
- C. D. Seppia, S. Ghione, P. Luschi, K. Ossenkopp, M. Kavaliers
- Medicine
- Neuroscience & Biobehavioral Reviews
- 31 December 2007
A substantial body of evidence has accumulated showing that exposure to electromagnetic fields (EMFs) affects pain sensitivity (nociception) and pain inhibition (analgesia). Consistent inhibitory… Expand
Antinociceptive effects of a pulsed magnetic field in the land snail, Cepaea nemoralis
- A. Thomas, M. Kavaliers, F. Prato, K. Ossenkopp
- Chemistry, Medicine
- Neuroscience Letters
- 31 January 1997
Pulsed magnetic fields (patent pending) consisting of approximately 100 microT (peak), frequency modulated, extremely low frequency magnetic fields (ELFMF) were shown to induce a significant degree… Expand
Sodium arsanilate-induced vestibular dysfunction in rats: Effects on open-field behavior and spontaneous activity in the automated digiscan monitoring system
- K. Ossenkopp, Anthony Prkacin, E. Hargreaves
- Medicine
- Pharmacology Biochemistry and Behavior
- 1 August 1990
Vestibular dysfunction was chemically induced in Long-Evans rats by intratympanic injections (30 mg per side) of sodium arsanilate (atoxyl). Following a one-week recovery period the rats were… Expand