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1q21

A chromosome band present on 1q
National Institutes of Health

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APOA1BP wt AlleleARNT wt AlleleCTSK wt AlleleChromosomes

Papers overview

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2018
2018
1q21扩增对硼替佐米治疗初治多发性骨髓瘤患者疗效和预后的影响
目的 探讨1q21扩增（简称1q）对硼替佐米（Btz）治疗多发性骨髓瘤（MM）疗效和预后的影响。 方法 以2009年11月至2016年8月180例初治MM患者为研究对象，比较伴与不伴1q的MM患者的临床特征，分析其对Btz疗效及患者预后的影响，并通过R2… 
2017
2017
DUF1220 Homo Sapiens and Neanderthal fractal periods architectures breakthrough
DUF1220 proteins regions show the largest Homosapiens lineage-specific increase in copy number of any protein- coding region in… 
2013
2013
Sinus Hypoplasia and Intracranial Hypertension in Pycnodysostosis (SHIHP): A New Disease Process? -
Pycnodysostosis is a rare autosomal recessive skeletal dysplasia caused by absence of active cathepsin K. Intracranial… 
2010
2010
Outcome with total therapy 3 (TT3) compared to total therapy 2 (TT2): Role of GEP70-defined high-risk disease with trisomy of 1q21 and activation of the proteasome gene PSMD4.
8027 Background: A GEP-based risk model (GEP70) defines 15% of newly diagnosed MM with a median survival of 2yr compared to 10+yr… 
2007
2007
Interferon-inducible IFI 16 protein in human cancers and autoimmune diseases
1. Abstract 2. Introduction 3. Regulation of IFI16 expression 3.1. Expression of IFI16 varies among individuals and may depend on… 
2001
2001
S100A2 coding sequence polymorphism: characterization and lack of association with psoriasis
Psoriasis is a chronic inflammatory skin disease with a strong genetic component. Linkage studies have identified several… 
1999
1999
Relationship between levels of leptin and hemoglobin in Japanese men.
To the Editor: Leptin, the ob gene product secreted by adipocyte, decreases food intake while it increases energy expenditure… 
1997
1997
A cytogenetically anchored genetic map of bovine chromosome 1 obtained by integrating flow-sorted chromosome-derived microsatellite markers into the international bovine map.
A genomic library was constructed from a peak of flow-sorted bovine chromosomes 1 + X after PCR amplification. Forty-three bovine… 
1977
1977
The relationship between sister chromatid exchanges and chromosome aberrations in Bloom's syndrome.
The distribution of the break points of sister chromatid exchanges (SCE) was compared with that of chromosome aberrations in… 
Highly Cited
1974
Highly Cited
1974
Familial mental retardation in a family with an inherited chromosome rearrangement
A family of three generations has been described with an insertional type of chromosome rearrangement involving chromosomes 11…