Skip to search formSkip to main contentSkip to account menu

NFKB2 gene

Known as: TRANSCRIPTION FACTOR NFKB2, LYMPHOCYTE TRANSLOCATION CHROMOSOME 10, NFKB2 
This gene plays a role in transcriptional regulation, signal transduction and inflammatory responses.
National Institutes of Health

Related topics

Related topics

17 relations
B-Cell LymphomasHomo sapiensImmune responseLeukemia, B-Cell

Narrower (1)

NFKB2 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
Clinical and Immunological Phenotype of Patients With Primary Immunodeficiency Due to Damaging Mutations in NFKB2
Non-canonical NF-κB-pathway signaling is integral in immunoregulation. Heterozygous mutations in NFKB2 have recently been… 
Highly Cited
2014
Highly Cited
2014
Mutations in NFKB2 and potential genetic heterogeneity in patients with DAVID syndrome, having variable endocrine and immune deficiencies
BackgroundDAVID syndrome is a rare condition combining anterior pituitary hormone deficiency with common variable… 
Highly Cited
2003
Highly Cited
2003
Treatment with an Anti-CD14 Monoclonal Antibody Delays and Inhibits Lipopolysaccharide-Induced Gene Expression in Humans in Vivo
CD14 is a receptor important for activation of cells by lipopolysaccharide (LPS). Treatment with the CD14 antibody IC14 was… 
Highly Cited
1994
Highly Cited
1994
Overproduction of NFKB2 (lyt-10) and c-Rel: a mechanism for HTLV-I Tax-mediated trans-activation via the NF-kappa B signalling pathway.
Molecular, biochemical and epidemiological evidence implicate HTLV-I as an etiologic agent of adult T cell leukemia (ATL). The… 
Highly Cited
1994
Highly Cited
1994
Mechanism of expression and role in transcriptional control of the proto-oncogene NFKB-2/LYT-10.
The NFKB-2 gene (previously LYT-10, NF-kappa Bp100 or NF-kappa Bp97) codes for a NF-kappa B/rel related protein which is highly… 
Highly Cited
1993
Highly Cited
1993
Chromosomal localization of genes encoding the transcription factors, c-rel, NF-kappa Bp50, NF-kappa Bp65, and lyt-10 by fluorescence in situ hybridization.
We have used fluorescence in situ hybridization (FISH) to perform precise chromosomal mapping of the genes encoding the… 
Highly Cited
1993
Highly Cited
1993
NF-kappa B p100 (Lyt-10) is a component of H2TF1 and can function as an I kappa B-like molecule
NF-kappa B is an important transcription factor regulating expression of genes involved in immune function, inflammation, and… 
Highly Cited
1993
Highly Cited
1993
Structural alterations of the NF-kappa B transcription factor lyt-10 in lymphoid malignancies.
We have previously reported the identification of a novel putative proto-oncogene involved in the breakpoint of a t(10;14)(q24… 
Highly Cited
1992
Highly Cited
1992
Distinct combinations of NF-kappa B subunits determine the specificity of transcriptional activation.
The nuclear factor that binds to the kappa light-chain enhancer of B cells (NF-kappa B) is a transcription factor that regulates… 
1991
1991
Cloning of an NF-kappa B subunit which stimulates HIV transcription in synergy with p65.
The transcription factor NF-kappa B is a protein complex which comprises a DNA-binding subunit and an associated transactivation… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)