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NFKB2 gene

Known as: TRANSCRIPTION FACTOR NFKB2, LYMPHOCYTE TRANSLOCATION CHROMOSOME 10, NFKB2 
This gene plays a role in transcriptional regulation, signal transduction and inflammatory responses.
National Institutes of Health

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Related topics

17 relations
B-Cell LymphomasHomo sapiensImmune responseLeukemia, B-Cell
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NFKB2 wt Allele

Papers overview

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2019
2019
Clinical and Immunological Phenotype of Patients With Primary Immunodeficiency Due to Damaging Mutations in NFKB2
Non-canonical NF-κB-pathway signaling is integral in immunoregulation. Heterozygous mutations in NFKB2 have recently been… Expand
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2014
2014
Mutations in NFKB2 and potential genetic heterogeneity in patients with DAVID syndrome, having variable endocrine and immune deficiencies
BackgroundDAVID syndrome is a rare condition combining anterior pituitary hormone deficiency with common variable… Expand
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2003
2003
Treatment with an Anti-CD14 Monoclonal Antibody Delays and Inhibits Lipopolysaccharide-Induced Gene Expression in Humans in Vivo
CD14 is a receptor important for activation of cells by lipopolysaccharide (LPS). Treatment with the CD14 antibody IC14 was… Expand
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1994
1994
Overproduction of NFKB2 (lyt-10) and c-Rel: a mechanism for HTLV-I Tax-mediated trans-activation via the NF-kappa B signalling pathway.
Molecular, biochemical and epidemiological evidence implicate HTLV-I as an etiologic agent of adult T cell leukemia (ATL). The… Expand
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1994
1994
Mechanism of expression and role in transcriptional control of the proto-oncogene NFKB-2/LYT-10.
The NFKB-2 gene (previously LYT-10, NF-kappa Bp100 or NF-kappa Bp97) codes for a NF-kappa B/rel related protein which is highly… Expand
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1993
1993
Chromosomal localization of genes encoding the transcription factors, c-rel, NF-kappa Bp50, NF-kappa Bp65, and lyt-10 by fluorescence in situ hybridization.
We have used fluorescence in situ hybridization (FISH) to perform precise chromosomal mapping of the genes encoding the… Expand
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Highly Cited
1993
Highly Cited
1993
Structural alterations of the NF-kappa B transcription factor lyt-10 in lymphoid malignancies.
We have previously reported the identification of a novel putative proto-oncogene involved in the breakpoint of a t(10;14)(q24… Expand
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1993
1993
NF-kappa B p100 (Lyt-10) is a component of H2TF1 and can function as an I kappa B-like molecule.
NF-kappa B is an important transcription factor regulating expression of genes involved in immune function, inflammation, and… Expand
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Highly Cited
1992
Highly Cited
1992
Distinct combinations of NF-kappa B subunits determine the specificity of transcriptional activation.
The nuclear factor that binds to the kappa light-chain enhancer of B cells (NF-kappa B) is a transcription factor that regulates… Expand
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1991
1991
Cloning of an NF-kappa B subunit which stimulates HIV transcription in synergy with p65.
The transcription factor NF-kappa B is a protein complex which comprises a DNA-binding subunit and an associated transactivation… Expand
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