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Somatostatin Receptor

Known as: receptor somatostatin, Receptors, SRIH, Receptors, Somatostatin 
Cell surface proteins that bind somatostatin and trigger intracellular changes which influence the behavior of cells. Somatostatin is a hypothalamic… 
National Institutes of Health

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Narrower (8)

BIM-23244Mch1r protein, ratSSTR2 protein, humansomatostatin receptor 1
Biological MarkersG Protein-Coupled Receptor SignalingG-Protein-Coupled ReceptorsIn Blood

Papers overview

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Highly Cited
2004
Highly Cited
2004
Agonist-dependent Dissociation of Human Somatostatin Receptor 2 Dimers
G-protein-coupled receptors (GPCRs) represent the largest and most diverse family of cell surface receptors. Several GPCRs have… 
Highly Cited
2004
Highly Cited
2004
Somatostatin inhibits IGF-1 mediated induction of VEGF in human retinal pigment epithelial cells.
Highly Cited
1999
Highly Cited
1999
Radiotherapy and dosimetry of 64Cu-TETA-Tyr3-octreotate in a somatostatin receptor-positive, tumor-bearing rat model.
64Cu [T1/2 = 12.8 h; beta+ = 0.655 MeV (19%); beta- = 0.573 MeV (40%)] has shown promise as a radioisotope for targeted… 
Highly Cited
1998
Highly Cited
1998
Immunocytochemical localization of somatostatin receptor sst2A in the rat spinal cord and dorsal root ganglia
Intrathecal administration of octreotide, a stable somatostatin analogue, provides pain relief in patients, and locally applied… 
Highly Cited
1998
Highly Cited
1998
Pre‐clinical comparison of [DTPA0] octreotide, [DTPA0,Tyr3] octreotide and [DOTA0,Tyr3] octreotide as carriers for somatostatin receptor‐targeted scintigraphy and radionuclide therapy
We have evaluated the potential usefulness of radiolabelled [DTPA0,Tyr3]octreotide and [DOTA0,Tyr3]octreotide as… 
Highly Cited
1998
Highly Cited
1998
[125I]Tyr10-cortistatin14 labels all five somatostatin receptors
The recently cloned rat preprocortistatin, which shows homology to the preprosomatostatin peptide, is thought to be enzymatically… 
Review
1992
Review
1992
In vitro detection of somatostatin receptors in human tumors.
Somatostatin receptors (SSR) have been identified in membrane homogenates or tissue sections from several hundred human tumors… 
Highly Cited
1990
Highly Cited
1990
Somatostatin receptors on human lymphocytes and leukaemia cells.
Receptors for somatostatin were identified on mitogen-activated human peripheral blood lymphocytes (PBL) and human leukaemic… 
Highly Cited
1985
Highly Cited
1985
Pertussis toxin blocks both cyclic AMP-mediated and cyclic AMP-independent actions of somatostatin. Evidence for coupling of Ni to decreases in intracellular free calcium.
Highly Cited
1985
Highly Cited
1985
Somatostatin receptors: Distribution in rat central nervous system and human frontal cortex
Somatostatins are a brain peptide family centered on a 14‐amino acid cyclic peptide (SS‐14) and a 28‐amino acid N‐terminally… 
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