Sensitization (observable entity)

Known as: Sensitization 
An increased in a behavioral response to a repeated stimulus. For example, a shock to the tail of the marine snail Aplysia, to which the snail… (More)
National Institutes of Health

Papers overview

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Review
2016
Review
2016
The role of calcitonin gene–related peptide in peripheral and central pain mechanisms including migraine
Calcitonin gene-related peptide (CGRP) is a 37-amino acid peptide found primarily in the C and Aδ sensory fibers arising from the… (More)
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Review
2011
Review
2011
Central sensitization: Implications for the diagnosis and treatment of pain
Nociceptor inputs can trigger a prolonged but reversible increase in the excitability and synaptic efficacy of neurons in central… (More)
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Highly Cited
2008
Highly Cited
2008
Neuropathic pain: redefinition and a grading system for clinical and research purposes.
Pain usually results from activation of nociceptive afferents by actually or potentially tissue-damaging stimuli. Pain may also… (More)
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Highly Cited
2004
Highly Cited
2004
Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase.
NF-kappaB is responsible for upregulating gene products that control cell survival. In this study, we demonstrate that SIRT1, a… (More)
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Highly Cited
2002
Highly Cited
2002
In vivo depletion of CD11c+ dendritic cells abrogates priming of CD8+ T cells by exogenous cell-associated antigens.
Cytotoxic T lymphocytes (CTL) respond to antigenic peptides presented on MHC class I molecules. On most cells, these peptides are… (More)
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Review
2001
Review
2001
Incentive-sensitization and addiction.
The question of addiction concerns the process by which drug-taking behavior, in certain individuals, evolves into compulsive… (More)
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Review
2001
Review
2001
The biology of human natural killer-cell subsets.
Human natural killer (NK) cells comprise approximately 15% of all circulating lymphocytes. Owing to their early production of… (More)
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Highly Cited
2001
Highly Cited
2001
Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta.
We show that high doses of salicylates reverse hyperglycemia, hyperinsulinemia, and dyslipidemia in obese rodents by sensitizing… (More)
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Highly Cited
1997
Highly Cited
1997
Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension
Abnormal smooth-muscle contractility may be a major cause of disease states such as hypertension, and a smooth-muscle relaxant… (More)
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Review
1991
Review
1991
The dendritic cell system and its role in immunogenicity.
Dendritic cells are a system of antigen presenting cells that function to initiate several immune responses such as the… (More)
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