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SUZ12 gene

Known as: KIAA0160, CHET9, SUPPRESSOR OF ZESTE 12, DROSOPHILA, HOMOLOG OF 
This gene plays a role in embryonic development and histone methylation.
National Institutes of Health

Related topics

Related topics

6 relations
Endometrial stromal noduleMethylationPolycomb Protein SUZ12Protein methylation

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SUZ12 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
H3K27me3 deficiency defines a subset of dedifferentiated chondrosarcomas with characteristic clinicopathological features
Dedifferentiated chondrosarcoma is a rare bone sarcoma, whose genetic background remains incompletely understood. Mutations in… 
Highly Cited
2016
Highly Cited
2016
Expression of ANRIL–Polycomb Complexes–CDKN2A/B/ARF Genes in Breast Tumors: Identification of a Two-Gene (EZH2/CBX7) Signature with Independent Prognostic Value
ANRIL, a long noncoding RNA (lncRNA), has recently been reported to have a direct role in recruiting polycomb repressive… 
Review
2016
Review
2016
Long Non-coding RNAs in Urologic Malignancies: Functional Roles and Clinical Translation
Early diagnosis and surveillance for metastasis and recurrences are critical issues of urologic cancer. Deregulation of long non… 
2016
2016
Long Non-coding RNA HOTAIR Expression in Diffuse Large B-Cell Lymphoma: In Relation to Polycomb Repressive Complex Pathway Proteins and H3K27 Trimethylation
Background A long non-coding RNA hox transcript antisense intergenic RNA (HOTAIR) is involved in epigenetic regulation through… 
2012
2012
Identification of recurrent type‐2 NF1 microdeletions reveals a mitotic nonallelic homologous recombination hotspot underlying a human genomic disorder
Nonallelic homologous recombination (NAHR) is one of the major mechanisms underlying copy number variation in the human genome… 
Highly Cited
2008
Highly Cited
2008
Expression Parameters of the Polycomb Group Proteins BMI1, SUZ12, RING1 and CBX7 in Urothelial Carcinoma of the Bladder and Their Prognostic Relevance
Background: The Polycomb group (PCG) proteins are epigenetic transcriptional repressors involved in the control of cellular… 
2007
2007
The Polycomb Group Protein SUZ12 regulates histone H3 lysine 9 methylation and HP1α distribution
Regulation of histone methylation is critical for proper gene expression and chromosome function. Suppressor of Zeste 12 (SUZ12… 
2005
2005
Extensively high load of internal tumors determined by whole body MRI scanning in a patient with neurofibromatosis type 1 and a non-LCR-mediated 2-Mb deletion in 17q11.2
Deletions in 17q11.2 affecting the NF1 gene and surrounding regions occur in 5% of patients with NF1. The two major types of NF1… 
2003
2003
Heterogeneity of breakpoints in non-LCR-mediated large constitutional deletions of the 17q11.2 NF1 tumour suppressor region
Neurofibromatosis type 1 (NF1) is caused by mutations of the NF1 gene at 17q11.2. The encoded protein, termed neurofibromin… 
2003
2003
Complete physical map and gene content of the human NF1 tumor suppressor region in human and mouse
Duplicon‐mediated microdeletions around the NF1 gene are frequently associated with a severe form of neurofibromatosis type I in… 
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