Polycomb Protein SUZ12

Known as: Suppressor of Zeste 12 Protein Homolog, Joined To JAZF1 Protein, Chet 9 Protein 
Polycomb protein SUZ12 (739 aa, ~83 kDa) is encoded by the human SUZ12 gene. This protein is a histone methyltransferase and plays a critical role in… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
In an inducible oncogenesis model, the miR-200 family is inhibited during CSC formation but not transformation, and inhibition of… (More)
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Highly Cited
2010
Highly Cited
2010
Polycomb proteins maintain cell identity by repressing the expression of developmental regulators specific for other cell types… (More)
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Highly Cited
2009
Highly Cited
2009
Polycomb group proteins have an essential role in the epigenetic maintenance of repressive chromatin states. The gene-silencing… (More)
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Highly Cited
2007
Highly Cited
2007
Polycomb group (PcG) proteins form multiprotein complexes, called Polycomb repressive complexes (PRCs). PRC2 contains the PcG… (More)
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Highly Cited
2007
Highly Cited
2007
Polycomb-repressive complex 2 (PRC2)-mediated histone methylation plays an important role in aberrant cancer gene silencing and… (More)
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Highly Cited
2006
Highly Cited
2006
The Polycomb group (PcG) proteins form chromatin-modifying complexes that are essential for embryonic development and stem cell… (More)
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Highly Cited
2005
Highly Cited
2005
PcG proteins mediate heritable transcriptional silencing by generating and recognizing covalent histone modifications. One… (More)
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Highly Cited
2004
Highly Cited
2004
SUZ12 is a recently identified Polycomb group (PcG) protein, which together with EZH2 and EED forms different Polycomb repressive… (More)
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Highly Cited
2004
Highly Cited
2004
Recent studies have revealed the intrinsic histone methyltransferase (HMTase) activity of the EED-EZH2 complex and its role in… (More)
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Highly Cited
2004
Highly Cited
2004
Polycomb group (PcG) complexes 2 and 3 are involved in transcriptional silencing. These complexes contain a histone lysine… (More)
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