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Polycomb Protein SUZ12

Known as: Suppressor of Zeste 12 Protein Homolog, Joined To JAZF1 Protein, Chet 9 Protein 
Polycomb protein SUZ12 (739 aa, ~83 kDa) is encoded by the human SUZ12 gene. This protein is a histone methyltransferase and plays a critical role in… 
National Institutes of Health

Related topics

Related topics

7 relations
Embryonic DevelopmentEnzyme GeneMethylationMethyltransferase Gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Tumor‐suppressive miR‐145 co‐repressed by TCF4‐β‐catenin and PRC2 complexes forms double‐negative regulation loops with its negative regulators in colorectal cancer
The frequently dysregulated Wnt/β‐catenin signaling in different malignancies, by activation of its own or orchestration with… 
2016
2016
CRISPR Cas9-guided chromatin immunoprecipitation identifies miR483 as an epigenetic modulator of IGF2 imprinting in tumors
The normally imprinted insulin-like growth factor II (IGF2) gene is aberrantly upregulated in a variety of human malignancies… 
2016
2016
An allosteric PRC 2 inhibitor targeting the H 3 K 27 me 3 binding pocket of EED
Wei Qi, Kehao Zhao, Justin Gu, Ying Huang, Youzhen Wang, Hailong Zhang, Maya Zhang, Jeff Zhang, Zhengtian Yu, Ling Li, Lin Teng… 
2015
2015
MiR-449a suppresses cell invasion by inhibiting MAP2K1 in non-small cell lung cancer.
Increasing evidence reveals that deregulation of miRNAs contributes to carcinogenesis of the human non-small cell lung cancer… 
2015
2015
Restoration of IGF2 imprinting by polycomb repressive complex 2 docking factor SUZ12 in colon cancer cells.
2013
2013
Polycomb repressive complex 2 (PRC2) suppresses Eμ-myc lymphoma.
Deregulation of polycomb group complexes polycomb repressive complex 1 (PRC1) and 2 (PRC2) is associated with human cancers… 
2012
2012
Mediator free cholesterol biosensor based on self-assembled monolayer platform.
Self-assembled monolayer (SAM) of 4-aminothiophenol (4-ATP) has been investigated for immobilization of bi-enzymes (ChOx and ChEt… 
2009
2009
Characterization of the expression pattern of the PRC2 core subunit Suz12 during embryonic development of Xenopus laevis
The Polycomb repressive complex 2 is a multimeric aggregate that mediates silencing of a broad range of genes, and is associated… 
Highly Cited
2008
Highly Cited
2008
Expression Parameters of the Polycomb Group Proteins BMI1, SUZ12, RING1 and CBX7 in Urothelial Carcinoma of the Bladder and Their Prognostic Relevance
Background: The Polycomb group (PCG) proteins are epigenetic transcriptional repressors involved in the control of cellular… 
2007
2007
Dithiobissuccinimidyl propionate self assembled monolayer based cholesterol biosensor.
A dithiobissuccinimidyl propionate (DTSP) self-assembled monolayer (SAM) prepared onto a gold (Au) surface has been utilized for… 
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