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Potential forensic application of DNA methylation profiling to body fluid identification
TLDR
Preliminary tests using methylation-specific PCR for the DACT1 and USP49 tDMRs showed that these two markers could be used successfully to identify semen samples including sperm cells. Expand
Protein kinase CK2alpha as an unfavorable prognostic marker and novel therapeutic target in acute myeloid leukemia.
  • J. Kim, J. Eom, +4 authors Y. Min
  • Medicine
  • Clinical cancer research : an official journal of…
  • 2007
TLDR
Findings strongly suggest protein kinase CK2alpha as an unfavorable prognostic marker and novel therapeutic target in AML. Expand
Body fluid identification in forensics.
TLDR
An overview of the present knowledge and the most recent developments in forensic body fluid identification is provided and its possible practical application to forensic casework is discussed. Expand
Protein Kinase CK2α as an Unfavorable Prognostic Marker and Novel Therapeutic Target in Acute Myeloid Leukemia
TLDR
The findings strongly suggest protein kinase CK2α as an unfavorable prognostic marker and novel therapeutic target in AML. Expand
DNA methylation-specific multiplex assays for body fluid identification
TLDR
Support is added to the support that body fluid identification by DNA methylation profiles could be a valuable tool for forensic analysis of body fluids. Expand
The Clinical Outcome of Chemotherapy-Induced Amenorrhea in Premenopausal Young Patients with Breast Cancer with Long-Term Follow-up
TLDR
Age and the addition of tamoxifen to the chemotherapy are the most important predictors of chemotherapy-induced amenorrhea in premenopausal patients with breast cancer with a positive hormone receptor. Expand
Clinical Outcomes and Prognosis of Recurrent Thymoma Management
TLDR
It is suggested that long-term surveillance extended at least 20 years may be essential for early detection of recurrence to increase the chance of complete re-resection of recurrent thymoma. Expand
Forensic and genetic characterization of mtDNA from Pathans of Pakistan
TLDR
The results suggest that frequency estimates for mtDNA haplotypes should be determined for endogamous ethnic groups individually instead of pooling data for these subpopulations into a single dataset for the Pakistani population. Expand
Body fluid identification by integrated analysis of DNA methylation and body fluid-specific microbial DNA
TLDR
Because the developed multiplex system uses the same biological source of DNA for individual identification profiling and simultaneously analyses various types of body fluid in one PCR reaction, this method will facilitate more efficient body fluid identification in forensic casework. Expand
Simple and highly effective DNA extraction methods from old skeletal remains using silica columns.
TLDR
A modified large-scale silica-based extraction combined with complete demineralization, that enables maximum DNA recovery and efficient elimination of PCR inhibitors is presented, that has successfully used to perform STR analysis for 55-year-old skeletal remains. Expand
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