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STK4 wt Allele

Known as: KRS2, Serine/Threonine Kinase 4 wt Allele, Kinase Responsive To Stress 2 Gene 
Human STK4 wild-type allele is located within 20q11.2-q13.2 and is approximately 113 kb in length. This allele, which encodes serine/threonine… 
National Institutes of Health

Related topics

Related topics

6 relations
ApoptosisMAPK Signaling PathwayPhosphorylationSerine/Threonine Phosphorylation

Broader (1)

STK4 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
mTORC2 regulates cardiac response to stress by inhibiting MST1.
Highly Cited
2013
Highly Cited
2013
Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2
Here we show that Mst1, a proapoptotic kinase, impairs protein quality control mechanisms in the heart through inhibition of… 
Highly Cited
2010
Highly Cited
2010
Mammalian Mst1 and Mst2 kinases play essential roles in organ size control and tumor suppression
Control of organ size by cell proliferation and survival is a fundamental developmental process, and its deregulation leads to… 
Highly Cited
2008
Highly Cited
2008
The Nore1B/Mst1 complex restrains antigen receptor-induced proliferation of naïve T cells
The Mst1 and Mst2 protein kinases are the mammalian homologs of hippo, a major inhibitor of cell proliferation in Drosophila… 
Highly Cited
2007
Highly Cited
2007
Frequent hypermethylation of MST1 and MST2 in soft tissue sarcoma
The RASSF1A tumor suppressor is involved in regulation of apoptosis and cell cycle progression. RASSF1A is localized to… 
Highly Cited
2006
Highly Cited
2006
Spatiotemporal regulation of the kinase Mst1 by binding protein RAPL is critical for lymphocyte polarity and adhesion
RAPL, a protein that binds the small GTPase Rap1, is required for efficient immune cell trafficking. Here we have identified the… 
Highly Cited
2006
Highly Cited
2006
Role of the tumor suppressor RASSF1A in Mst1-mediated apoptosis.
Mammalian sterile 20-like kinase 1 (Mst1) is activated by both caspase-mediated cleavage and phosphorylation in response to… 
Highly Cited
2004
Highly Cited
2004
Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras.
MST1 (mammalian Sterile20-like 1) and MST2 are closely related Class II GC (protein Ser/Thr) kinases that initiate apoptosis when… 
Highly Cited
2001
Highly Cited
2001
Both Phosphorylation and Caspase-mediated Cleavage Contribute to Regulation of the Ste20-like Protein Kinase Mst1 during CD95/Fas-induced Apoptosis*
The serine/threonine kinase Mst1, a mammalian homolog of the budding yeast Ste20 kinase, is cleaved by caspase-mediated… 
Highly Cited
1998
Highly Cited
1998
Caspase‐mediated activation and induction of apoptosis by the mammalian Ste20‐like kinase Mst1
Mst1 is a ubiquitously expressed serine–threonine kinase, homologous to the budding yeast Ste20, whose physiological regulation… 
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