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STK4 wt Allele

Known as: KRS2, Serine/Threonine Kinase 4 wt Allele, Kinase Responsive To Stress 2 Gene 
Human STK4 wild-type allele is located within 20q11.2-q13.2 and is approximately 113 kb in length. This allele, which encodes serine/threonine… 
National Institutes of Health

Related topics

Related topics

6 relations
ApoptosisMAPK Signaling PathwayPhosphorylationSerine/Threonine Phosphorylation

Broader (1)

STK4 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
Long non-coding RNA ROR sponges miR-138 to aggravate hypoxia/reoxygenation-induced cardiomyocyte apoptosis via upregulating Mst1.
2016
2016
Early protective role of MST1 knockdown in response to experimental diabetic nephropathy.
Diabetic nephropathy (DN) is a progressive kidney disease caused by the damage of capillaries in kidney's glomeruli. Mammalian… 
2016
2016
Mst 1 regulates hepatic lipid metabolism by inhibiting Sirt 1 ubiquitination in mice
Previous study showed mammalian Ste20-like kinase (Mst1) may serve as target for the development of new therapies for diabetes… 
2016
2016
168 Targeting The Hippo Signalling Pathway to Enhance the Therapeutic Potential of iPS-Derived Cardiomyocytes
Introduction Cell based therapy using stem cell derived cardiomyocytes, has emerged as a potential therapeutic approach for… 
2014
2014
PHLPP1 regulates contact inhibition by dephosphorylating Mst1 at the inhibitory site.
2014
2014
Activation of Pro-survival CaMK4β/CREB and Pro-death MST1 signaling at early and late times during a mouse model of prion disease
The signaling pathways most critical to prion disease pathogenesis are as yet incompletely characterized. We have developed a… 
2011
2011
24 A novel anti-hypertrophic pathway in cardiomyocytes regulated by the tumour suppressor mammalian STE20-like kinase 1 (Mst1)
The mammalian STE20-like kinase 1 (Mst1) is a pro-apoptotic kinase implicated in organ size control and tumour suppression. We… 
2010
2010
MST 1 Promotes Apoptosis through Phosphorylation of Histone H 2 AX *
MST1 (mammalian STE20-like kinase 1) is a serine/threonine kinase that is cleaved and activated by caspases during apoptosis… 
2009
2009
[Overexpression of hSav1 promotes Mst1-induced apoptosis in HeLa cells].
OBJECTIVE To elucidate the effect of hSav1 expression on Mst1-mediated apoptosis in HeLa cells. METHODS Plasmids pCMV-HA-hSav1… 
1999
1999
Role of a serine/threonine kinase, Mst1, in megakaryocyte differentiation
Platelets, which play a central role in thrombosis and hemostasis, develop from megakaryocytes. Signal transduction originated… 
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