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SRSF1 gene

Known as: SPLICING FACTOR, ARGININE/SERINE-RICH, 30-KD, A, ALTERNATIVE SPLICING FACTOR, SR splicing factor 1 
This gene is involved in both RNA processing and transport.
National Institutes of Health

Related topics

Related topics

16 relations
Homo sapiensIntracellular TransportLigand BindingMolecular Transport

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2006
Review
2006
Rad54: the Swiss Army knife of homologous recombination?
Homologous recombination (HR) is a ubiquitous cellular pathway that mediates transfer of genetic information between homologous… 
Highly Cited
2005
Highly Cited
2005
Structure of the SWI2/SNF2 chromatin-remodeling domain of eukaryotic Rad54
SWI2/SNF2 chromatin-remodeling proteins mediate the mobilization of nucleosomes and other DNA-associated proteins. SWI2/SNF2… 
Highly Cited
1997
Highly Cited
1997
Phosphorylation of the ASF/SF2 RS domain affects both protein-protein and protein-RNA interactions and is necessary for splicing.
ASF/SF2 is a member of a conserved family of splicing factors known as SR proteins. These proteins, which are necessary for… 
Highly Cited
1997
Highly Cited
1997
Protection of chimpanzees from high-dose heterologous HIV-1 challenge by DNA vaccination
Novel approaches for the generation of more effective vaccines for HIV-1 are of significant importance. In this report we analyze… 
Highly Cited
1997
Highly Cited
1997
The splicing factor SRp20 modifies splicing of its own mRNA and ASF/SF2 antagonizes this regulation
SRp20 is a member of the highly conserved SR family of splicing regulators. Using a variety of reporter gene constructs, we show… 
Highly Cited
1997
Highly Cited
1997
Both phosphorylation and dephosphorylation of ASF/SF2 are required for pre-mRNA splicing in vitro.
The splicing reaction that removes introns from pre-messenger RNAs requires the assembly of the spliceosome on the nascent… 
Highly Cited
1996
Highly Cited
1996
Targeted disruption of an essential vertebrate gene: ASF/SF2 is required for cell viability.
Alternative splicing factor/splicing factor 2 (ASF/SF2) is the prototype of a family of nuclear proteins highly conserved… 
Highly Cited
1991
Highly Cited
1991
An IgG human monoclonal antibody that reacts with HIV-1/GP120, inhibits virus binding to cells, and neutralizes infection.
A human mAb (HmAb) termed F105 was obtained by fusion of antibody-producing EBV-transformed cells with the HMMA2.11TG/O cell line… 
Highly Cited
1991
Highly Cited
1991
Human immunodeficiency virus infection of human-PBL-SCID mice.
Severe combined immunodeficient (SCID) mice reconstituted with human peripheral blood leukocytes (hu-PBL-SCID mice) have… 
Highly Cited
1985
Highly Cited
1985
Multiple factors including the small nuclear ribonucleoproteins U1 and U2 are necessary for Pre-mRNA splicing in vitro
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